Nakazawa Naotaka

Affiliation and department：
Homepage URL (1)： https://nakazawalab.com/

Research field (6)： Structural and functional materials , Neuroscience - general , Cell biology , Developmental biology , Biophysics , Biomedical engineering

Research keywords (5)： Intracellular signal transduction , Mechanobiology , Cytoskeleton , Morphogenesis , Biomechanics

Research theme for competitive and other funds (8)：

2023 - 2025 A study on a mechanobiological element based on mechanoseinsing in the neuron
2021 - 2024 プレッシオ脳神経科学の促進・発展
2021 - 2024 脳脊髄液圧依存的な組織伸展と神経幹細胞への圧縮刺激による神経発生の調節機構の解明
2018 - 2022 新規素材とマイクロ加工技術で再現する脳微小空間を用いたニューロン遊走機構の解析
2018 - 2022 ニューロン遊走における細胞核弾性率の調節機構およびDNA損傷保護機構の解明

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Papers (19)：

Tanita Frey, Tomonari Murakami, Koichiro Maki, Takumi Kawaue, Naoki Tani, Ayaka Sugai, Naotaka Nakazawa, Kei-ichiro Ishiguro, Taiji Adachi, Mineko Kengaku, et al. Age-associated reduction of nuclear shape dynamics in excitatory neurons of the visual cortex. Aging Cell. 2023
Yi-Ting Lai, Sasamura Takeshi, Junpei Kuroda, Reo Maeda, Mitsutoshi Nakamura, Ryo Hatori, Tomoki Ishibashi, Kiichiro Taniguchi, Masashi Ooike, Tomohiro Taguchi, et al. The Drosophila AWP1 ortholog Doctor No regulates JAK/STAT signaling for left-right asymmetry in the gut by promoting receptor endocytosis. Development (Cambridge, England). 2023. 150. 6
Hiroaki Hirata, Naotaka Nakazawa, Tsuyoshi Hirashima, Andrea Ravasio. Editorial: Multicellularity: Views from cellular signaling and mechanics. Frontiers in cell and developmental biology. 2023. 11. 1172921-1172921
Yotaro Ochi, Ayana Kon, Toyonori Sakata, Masahiro M Nakagawa, Naotaka Nakazawa, Masanori Kakuta, Keisuke Kataoka, Haruhiko Koseki, Manabu Nakayama, Daisuke Morishita, et al. Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes. Cancer discovery. 2020. 10. 6. 836-853
Bo Yang, Haguy Wolfenson, Vin Yee Chung, Naotaka Nakazawa, Shuaimin Liu, Junqiang Hu, Ruby Yun-Ju Huang, Michael P Sheetz. Stopping transformed cancer cell growth by rigidity sensing. Nature materials. 2020. 19. 2. 239-250

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MISC (8)：

Naotaka Nakazawa, Gianluca Grenci, Yoshitaka Kameo, Noriko Takeda, Tsuyoshi Sawada, Junko Kurisu, Zhejing Zhang, Taiji Adachi, Keiko Nonomura, Mineko Kengaku. Migrating neurons adapt motility modes to brain microenvironments via a mechanosensor, PIEZO1. 2023
Tanita Frey, Tomonari Murakami, Koichiro Maki, Takumi Kawaue, Ayaka Sugai, Naotaka Nakazawa, Taiji Adachi, Mineko Kengaku, Kenichi Ohki, Yukiko Gotoh, et al. Age-associated reduction of nuclear shape dynamics in excitatory neurons of the visual cortex. 2022
Yi-Ting Lai, Sasamura Takeshi, Junpei Kuroda, Reo Maeda, Mitsutoshi Nakamura, Ryo Hatori, Tomoki Ishibashi, Kiichiro Taniguchi, Masashi Ooike, Tomohiro Taguchi, et al. The Drosophila AWP1 ortholog Doctor No regulates JAK/STAT signaling for left-right asymmetry in the gut by promoting receptor endocytosis. 2022
中澤直高, 見学美根子. 【メカノバイオロジー】力学環境依存的な細胞の機能発現脳発生に寄与するニューロン遊走のメカノバイオロジー. 生体の科学. 2019. 70. 4. 317-321
Bo Yang, Haguy Wolfenson, Naotaka Nakazawa, Shuaimin Liu, Junqiang Hu, Michael P. Sheetz. Stopping Transformed Growth with Cytoskeletal Proteins: Turning a Devil into an Angel. 2017

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Books (3)：

Multicellularity: Views from cellular signaling and mechanics
Frontiers in Cell and Developmental Biology 2023 ISBN:9782832520260
カンデル神経科学
メディカル・サイエンス・インターナショナル 2022 ISBN:9784815730550
留学先における体験談-人間関係にフォーカスして-
実験医学 2015

Lectures and oral presentations (20)：

狭小な空間内を遊走する新生ニューロンがもつ力学刺激に対する検知・応答機構
(第46回日本分子生物学会年会 2023)
Molecular mechanisms of mechano-sensing / -response for neuronal migration in 3D brain tissue
(2022)
Molecular mechanisms of mechano-sensing / -response for neuronal migration in 3D brain tissue
(2022)
Mechanical stress by extracellular confinement triggers a mode transition of neuronal migration
(Materials, Mimics, and Microfluidics: Engineering Tools for Mechanobiology (MBI 3M) 2021)
Mechanical stress by extracellular confinement trigger a mode transition of neuronal migration
(The 58th Annual Meeting of the Biophysical Society of Japan 2020)

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Education (2)：

2008 - 2013 Tokyo University of Science Graduate School of Industrial Science and Technology
2004 - 2008 Tokyo University of Science Faculty of Industrial Science and Technology Biological Science and Technology

Professional career (1)：

博士(工学) (東京理科大学)

Work history (7)：

2023/04 - 現在 Japan Science and Technology Agency
2022/04 - 現在 Kindai University Faculty of Science and Engineering
2022/04 - 現在 Kyoto University Institute for Integrated Cell-Material Sciences
2017/06 - 2022/03 Kyoto university Institute for integrated Cell-Material Sciences Program-Specific Assistant Professor
2017/03 - 2017/06 Kyoto university Institute for integrated Cell-Material Sciences Program-Specific Research Associate

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Awards (3)：

2018/07 - 新学術領域「脳構築における発生時計と場の連携」第3回班会議優秀ポスター賞
2016/12 - 日本分子生物学会海外若手研究者招聘企画
2012/09 - 第2回モデル生物丸ごと一匹学会優秀発表賞

Association Membership(s) (2)：

日本分子生物学会 , 日本生物物理学会

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