Research theme for competitive and other funds (5):
2023 - 2027 Structural profiling of fungal cell wall polysaccharides using functionally modified glycoside hydrolase
2024 - 2025 機能改変酵素を用いた抗真菌薬探索基盤の構築
2020 - 2023 機能改変酵素を用いた革新的真菌感染症診断法の実用化開発
2018 - 2019 エンドグルカナーゼの機能改変による真菌感染症迅速診断法の開発
2015 - 2017 酵素合成リグニンポリマーを応用した非侵襲性新規免疫アジュバントの開発
Papers (53):
Rui Tada, Hiroki Ito, Yuzuho Nagai, Yasuhiro Sakurai, Daisuke Yamanaka, Naohito Ohno, Jun Kunisawa, Yoshiyuki Adachi, Yoichi Negishi. Addition of mucoadhesive agent to enzymatically polymerized caffeic acid-based nasal vaccine formulation attenuates antigen-specific antibody responses in mice. International Journal of Medicinal Mushrooms. 2024. 26. 10. 1-8
Keijiro Mizukami, Angella Dorsey-Oresto, Karthik Raj, Anna Eringis, Eva Furrow, Errolyn Martin, Daisuke Yamanaka, Alexandra Kehl, Ana Kolicheski, Vidhya Jagannathan, et al. Increased susceptibility to Mycobacterium avium complex infection in miniature Schnauzer dogs caused by a codon deletion in CARD9. Scientific reports. 2024. 14. 1. 10346-10346
Jigar V Desai, Marissa A Zarakas, Andrew L Wishart, Mark Roschewski, Mariano A Aufiero, Ágnes Donkó, Gustaf Wigerblad, Neta Shlezinger, Markus Plate, Matthew R James, et al. BTK drives neutrophil activation for sterilizing antifungal immunity. The Journal of clinical investigation. 2024
Rui Tada, Yuzuho Nagai, Miki Ogasawara, Momoko Saito, Akihiro Ohshima, Daisuke Yamanaka, Jun Kunisawa, Yoshiyuki Adachi, Yoichi Negishi. Polymeric Caffeic Acid Acts as an Antigen Delivery Carrier for Mucosal Vaccine Formulation by Forming a Complex with an Antigenic Protein. Vaccines. 2024. 12. 5. 449-449
Akitomo Motoi, Katsuya Tajima, Masuro Motoi, Katsuaki Nishihara, Daisuke Yamanaka, Ken-Ichi Ishibashi, Naohito Ohno, Yoshiyuki Adachi. Effects of Outdoor-Grown Royal Sun Medicinal Mushroom Agaricus brasiliensis KA21 (Agaricomycetes) Fruiting Body on Canine Malassezia Dermatitis. International journal of medicinal mushrooms. 2024. 26. 6. 13-23
山中大輔. Development of sensitive glucan detection system using functionally-modified glycoside hydrolase. 日本細菌学雑誌(Web). 2022. 77. 1
山中大輔, 栗田涼香, 菅野峻史, 安達禎之. Development of novel structure-specific detection method for β-1,3/1,6-glucan using split-NanoLuc-fused β-glucan binding proteins. 日本薬学会年会要旨集(Web). 2022. 142nd