Nagai Hiroki

ナガイヒロキ | Nagai Hiroki

Affiliation and department：

Research field (1)： Bacteriology

Research theme for competitive and other funds (23)：

2022 - 2024 アメーバをめぐるポストコッホ微生物生態学
2019 - 2023 アメーバ共生系を基盤とする新規微生物の探索
2020 - 2022 アメーバをめぐるポストコッホ微生物生態学
2019 - 2022 Tn-seqを活用したレジオネラ病原性研究の新展開
2015 - 2018 High-throughput screening for chemical compounds which restict intracellular bacteria

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Papers (74)：

Tomoko Kubori, Kohei Arasaki, Tomoe Kitao, Hiroki Nagai. Multi-tiered actions of Legionella effectors to modulate host Rab10 dynamics. 2023
Jonathan Pruneda, Justine V. Nguyen, Hiroki Nagai, Tomoko Kubori. Bacterial usurpation of the OTU deubiquitinase fold. The FEBS Journal. 2023
Gus D. Warren, Tomoe Kitao, Tyler G. Franklin, Justine V. Nguyen, Paul P. Geurink, Tomoko Kubori, Jonathan Pruneda. Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA. Molecular Cell. 2022. 83. 1. 105-120.e5
Shoichi Mitsunaka, Kohei Yamazaki, Ajeng K. Pramono, Megumi Ikeuchi, Tomoe Kitao, Naoya Ohara, Tomoko Kubori, Hiroki Nagai, Hiroki Ando. Synthetic engineering and biological containment of bacteriophages. Proceedings of the National Academy of Sciences. 2022. 119. 48
Tomoko Kubori, Junyup Lee, Hyunmin Kim, Kohei Yamazaki, Masanari Nishikawa, Tomoe Kitao, Byung-Ha Oh, Hiroki Nagai. Reversible modification of mitochondrial ADP/ATP translocases by paired Legionella effector proteins. Proceedings of the National Academy of Sciences. 2022. 119. 23

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MISC (6)：

島守祐月, 大原直也, 露口一成, 大屋賢司, 吉田志緒美, 武田茂樹, 永井宏樹, 安藤弘樹. マイコファージによる非結核性抗酸菌症の予防法と治療法の確立. 日本細菌学雑誌. 2019. 74. 1. 51-51
島守祐月, 大原直也, 露口一成, 大屋賢司, 吉田志緒美, 武田茂樹, 永井宏樹, 安藤弘樹. マイコファージによる非結核性抗酸菌症の予防法と治療法の確立. 日本細菌学雑誌. 2019. 74. 1. 51-51
平安恒幸, 齋藤史路, 末永忠広, 信田京子, 荒瀬規子, 及川敬太, 山岡俊文, 室田浩之, 知花博治, 中川一路, et al. HLAクラスI認識受容体群LILRの新展開病原微生物によって壊された抗体を認識する生体防御機構. MHC: Major Histocompatibility Complex. 2016. 23. 2Suppl. 95-95
YAMAGUCHI HIROYUKI, MATSUO JUNJI, SEKIZUKA TSUYOSHI, KURODA MAKOTO, NAGAI HIROKI, SUGIMOTO CHIHIRO. Comparative genomics of primitive chlamydiae showing distinct mutualistic symbiosis with amoebae. 日本細菌学雑誌. 2013. 68. 1. 186
百武晃宏, 久堀智子, 永井宏樹. レジオネラの宿主細胞内増殖に関わる新規エフェクターの同定とその機能解析. 日本細菌学雑誌. 2007. 62. 1. 101-101

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Books (36)：

実験医学 Vol.33 病原菌の侵入・増殖と宿主真核細胞の攻防
羊土社 2015
呼吸器内科 Vol.26 レジオネラ症とその病原メカニズムをめぐる新展開
科学評論社 2014
Nihon Saikingaku Zasshi Vol.69 The host-pathogen interaction of Legionella pneumophila.
2014
Methods Mol Biol Vol.1197 Hijacking the host proteasome for the temporal degradation of bacterial effectors.
2014 ISBN:9781493912612
Methods Mol Biol Vol.954 Purification and characterization of legionella u-box-type e3 ubiquitin ligase.
2013 ISBN:9781627031615

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Lectures and oral presentations (34)：

T4BSS: a pivotal tool to establish intracellular lifestyle of bacteria
(5th International Symposium of the Collaborative Research Centre 766 (SFB766) 2017)
Manipulation of the host ubiquitin system by Legionella Deubiquitinases.
(Type iV secretion in gram-negative and gram-positive bacteria 2016 2016)
T4BSS: a pivotal tool to establish intracellular lifestyle of bacteria
(Type iV secretion in gram-negative and gram-positive bacteria 2016 2016)
レジオネラの分泌装置とエフェクターから紐解く感染細胞内での卓越した宿主細胞支配機構
(第31回日本微生物生態学会大会 2016)
Manipulation of the host ubiquitin system by Legionella Deubiquitinases.
(第15回あわじしま感染症・免疫フォーラム 2016)

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Professional career (1)：

Awards (1)：

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