Ken Takashima

タカシマケン | Ken Takashima

Affiliation and department：

Research field (3)： Genetics , Molecular biology , Immunology

Research keywords (5)：ヒストン修飾 , 腫瘍医学 , エピジェネティクス , 免疫学 , Molecular Biology

Research theme for competitive and other funds (8)：

2024 - 2026 「内在性ヒストン模倣分子」による免疫応答の制御機構の解明
2022 - 2024 B細胞の分化・機能の制御における「内在性ヒストン模倣因子」の役割
2022 - 2024 天然変性タンパク質による「ヒストン模倣」現象の作動原理の解明
2022 - 2024 Role of a novel histone modification regulator in immune response
2021 - 2023 乳癌の形成・進展における新規ヒストン修飾制御因子の役割

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Papers (17)：

Mako Yamaguchi, Yohana S Mtali, Hitomi Sonokawa, Ken Takashima, Yoshimi Fukushima, Takahisa Kouwaki, Hiroyuki Oshiumi. HPV vaccines induce trained immunity and modulate pro-inflammatory cytokine expression in response to secondary Toll-like receptor stimulations. Microbiology and immunology. 2023
Ken Takashima, Dian-Jang Lee, María Fernanda Trovero, M Hafiz Rothi, Meeta Mistry, Ying Zhang, Zhouyihan Li, Christopher P Davis, Zilan Li, Julia Natale, et al. NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression. bioRxiv : the preprint server for biology. 2023
Yusuke Miyashita, Takanobu Yoshida, Yuriko Takagi, Hirotake Tsukamoto, Ken Takashima, Takahisa Kouwaki, Katsunari Makino, Satoshi Fukushima, Kimitoshi Nakamura, Hiroyuki Oshiumi. Circulating extracellular vesicle microRNAs associated with adverse reactions, proinflammatory cytokine, and antibody production after COVID-19 vaccination. NPJ vaccines. 2022. 7. 1. 16-16
Simon Yuan Wang, Elizabeth Ann Pollina, I-Hao Wang, Lindsay Kristina Pino, Henry L Bushnell, Ken Takashima, Colette Fritsche, George Sabin, Benjamin Aaron Garcia, Paul Lieberman Greer, et al. Role of epigenetics in unicellular to multicellular transition in Dictyostelium. Genome biology. 2021. 22. 1. 134-134
Konstantinos Boulias, Diana Toczydłowska-Socha, Ben R Hawley, Noa Liberman, Ken Takashima, Sara Zaccara, Théo Guez, Jean-Jacques Vasseur, Françoise Debart, L Aravind, et al. Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome. Molecular cell. 2019. 75. 3. 631-643

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MISC (2)：

高島謙, 押海裕之. The innate immune response to SARS-CoV-2. ウイルス. 2021. 71. 1
高島謙, 押海裕之. Regulation of immunoglobulin production in Golgi apparatus. 月刊臨床免疫・アレルギー科. 2021. 76. 6

Lectures and oral presentations (1)：

免疫応答の制御における核小体・エピジェネティクス恒常性維持の意義
(第10回免疫若手アカデミー勉強会(若手向き勉強会) 2023)

Education (2)：

2014 - 2017 Hokkaido university Graduated school MD-PhD program
2008 - 2014 Hokkaido university

Professional career (1)：

医学博士 (北海道大学)

Work history (4)：

2021/05 - 現在 Kumamoto University Faculty of Life Sciences
2021/04 - 2021/04 Kumamoto University Faculty of Life Sciences
2018/04 - 2021/03 Harvard Medical School / Boston Children's Hospital Newborn Medicine Postdoctoral fellow
2017/04 - 2018/04 北海道大学大学院医学研究院特任助教

Association Membership(s) (6)：

THE JAPANESE BIOCHEMICAL SOCIETY , 日本インターフェロン・サイトカイン学会 , THE JAPANESE SOCIETY FOR IMMUNOLOGY , 日本エピジェネティクス研究会 , 日本分子生物学会 , 日本生体防御学会

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