Research field (5):
Genomics
, Pharmaceuticals - chemistry and drug development
, Environmental effects of chemicals
, Environmental effects of radiation
, Tumor biology
2018 - 2020 Study on novel mechanism of breast cancer development by modulation of mitochondrial control
2018 - 2020 Development of radiation sensitization for cancer cells based on cell cycle-dependent DNA repair system
2017 - 2019 S/G2期における放射線感受性を高める因子の同定とがん治療開発へ向けた研究
2015 - 2017 効率的な細胞老化促進によるがん抑制法の基礎研究
2012 - 2016 Basic research to explore factors to improve effectiveness of radiation therapy
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Papers (18):
Qianqian Guo, Shuting Ji, Kazuma Takeuchi, Wataru Urasaki, Asuka Suzuki, Yusuke Iwasaki, Hiroko Saito, Zeyu Xu, Masami Arai, Seigo Nakamura, et al. Functional evaluation of BRCA1/2 variants of unknown significance with homologous recombination assay and integrative in silico prediction model. Journal of Human Genetics. 2023
Doudou Zhang, Takashi Shimokawa, Qianqian Guo, Shingo Dan, Yoshio Miki, Shigeaki Sunada. Discovery of novel DNA-damaging agents through phenotypic screening for DNA double-strand break. Cancer science. 2023. 114. 3. 1108-1117
Shigeaki Sunada, Yoshio Miki. PARP Inhibitors: Mechanism of Action. Hereditary Breast and Ovarian Cancer. 2021. 281-292
Shigeaki Sunada, Hiroko Saito, Doudou Zhang, Zeyu Xu, Yoshio Miki. CDK1 inhibitor controls G2/M phase transition and reverses DNA damage sensitivity. Biochemical and biophysical research communications. 2021. 550. 56-61
Guillaume Vares, Vidhula Ahire, Shigeaki Sunada, Eun Ho Kim, Sei Sai, François Chevalier, Paul-Henri Romeo, Tadashi Yamamoto, Tetsuo Nakajima, Yannick Saintigny. A multimodal treatment of carbon ions irradiation, miRNA-34 and mTOR inhibitor specifically control high-grade chondrosarcoma cancer stem cells. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2020. 150. 253-261