Rchr
J-GLOBAL ID：201701008904765530
Update date: Oct. 30, 2024
Tanino Hirokazu
タニノ ヒロカズ | Tanino Hirokazu
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
https://breastlife2020.com
Research field (1)：
Tumor diagnostics and therapeutics
Research keywords (6)：
TearExo
, BRCAness
, PDX
, xenograft
, exosome
, Triple negative breast cancer
Research theme for competitive and other funds (5)：
- 2021 - 2024 Subset cell analysis of gynecological cancer-associated fibroblast that induce lymph node metastasis.
- 2021 - 2024 Development and application of an early detection method for postoperative recurrence of colorectal cancer using tears
- 2021 - 2024 涙液を用いた新しい乳癌早期診断法の確立
- 2021 - 2024 がん早期診断における涙液エクソソームの有用性の検討
- 2020 - 2023 miR-622内包人工エクソソームによる卵巣癌の浸潤・転移と微小環境制御
Papers (42)：
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Sachiko Inubushi, Tomonari Kunihisa, Marina Kuniyasu, Shotaro Inoue, Mayuko Yamamoto, Yuji Yamashita, Mayuko Miki, Sachiko Mizumoto, Motoi Baba, Robert M Hoffman, et al. Serum Exosomes Expressing CD9, CD63 and HER2 From Breast-Cancer Patients Decreased After Surgery of the Primary Tumor: A Potential Biomarker of Tumor Burden. Cancer genomics & proteomics. 2024. 21. 6. 580-584
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Tomonari Kunihisa, Sachiko Inubushi, Hirokazu Tanino, Robert M Hoffman. Induction of the DNA-Repair Gene POLQ only in BRCA1-mutant Breast-Cancer Cells by Methionine Restriction. Cancer genomics & proteomics. 2024. 21. 4. 399-404
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Sachiko Mizumoto, Sachiko Inubushi, Mayuko Miki, Haruna Nakamura, Motoi Baba, Yuji Yamashita, Mayuko Yamamoto, Shotaro Inoue, Hirokazu Tanino, Tomonari Kunihisa. Target-Oriented Classification of Triple-negative Breast Cancer. Anticancer research. 2023. 43. 11. 5067-5072
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Chihiro Wakayama, Sachiko Inubushi, Tomonari Kunihisa, Sachiko Mizumoto, Motoi Baba, Hirokazu Tanino, Ik Sung Cho, Tooru Ooya. Protein corona formation on epigallocatechin gallate-Au nanoparticles suppressed tumor accumulation. JCIS Open. 2023. 9
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Sachiko Inubushi, Tomonari Kunihisa, Sachiko Mizumoto, Shotaro Inoue, Mayuko Miki, Atsushi Suetsugu, Hirokazu Tanino, Robert M Hoffman. Methionine Restriction Increases Exosome Production and Secretion in Breast Cancer Cells. Cancer genomics & proteomics. 2023. 20. 5. 412-416
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MISC (16)：
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Sachiko Inubushi, Hiroki Kawaguchi, Sachiko Mizumoto, Tomonari Kunihisa, Motoi Baba, Yukiya Kitayama, Toshifumi Takeuchi, Robert M. Hoffman, Hirokazu Tanino, Ryohei Sasaki. Oncogenic miRNAs Identified in Tear Exosomes From Metastatic Breast Cancer Patients (vol 40, pg 3091, 2020). ANTICANCER RESEARCH. 2020. 40. 8. 4805-4805
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谷野 裕一, 鈴木 正人, 海瀬 博史, 宮下 勝, 千島 隆司, 林 光弘, 三好 康雄, 二村 学, 大谷 彰一郎, 永橋 昌幸, et al. 日本における新規乳がん治療薬の開発 トリプルネガティブ乳癌治療のコンパニオン診断薬開発とカルボプラチンの再発抑制効果の第3相臨床試験. 日本乳癌学会総会プログラム抄録集. 2019. 27回. 277-277
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Yoshimasa Kosaka, Naoko Minatani, Yoko Tanaka, Akiko Shida, Mariko Kikuchi, Hiroshi Nishimiya, Mina Waraya, Hiroshi Katoh, Takeo Sato, Norihiko Sengoku, et al. Lymph node metastasis and high serum CEA are important prognostic factors in hormone receptor positive and HER2 negative breast cancer. Molecular and clinical oncology. 2018. 9. 5. 566-574
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小坂 愉賢, 菊池 真理子, 信太 昭子, 岡本 光祈子, 田中 蓉子, 加藤 弘, 梶田 咲美乃, 谷野 裕一, 山本 豊, 明石 定子, et al. 「それぞれの癌」難治性癌に対する治療戦略 乳腺 トリプルネガティブ乳癌の治療成績と今後の治療戦略. 日本癌治療学会学術集会抄録集. 2017. 55回. WS13-5
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信太 昭子, 小坂 愉賢, 藁谷 美奈, 田中 蓉子, 菊池 真理子, 南谷 菜穂子, 加藤 弘, 仙石 紀彦, 谷野 裕一, 渡邊 昌彦. 第30回北里腫瘍フォーラム 新規タキサン系抗悪性腫瘍薬による発疹に関する検討. 北里医学 = Kitasato medicine. 2016. 46. 2. 123-127
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Lectures and oral presentations (10)：
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Risk analysis for chemotherapy induced nausea and vomiting (CINV) in patients receiving FEC100 treatment
(SAN ANTONIO BREAST CANCER SYMPOSIUM 43rd Annual SABCS 2018)
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Phase 3 trial of carboplatin in triple negative breast cancer (TNBC) patients with residual invasive carcinoma after neoadjuvant chemotherapy (JONIE4:J-CAT trial)
(SAN ANTONIO BREAST CANCER SYMPOSIUM 43rd Annual SABCS 2018)
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BRCAness as a prognostic marker in triple-negative breast cancer patients treated with neoadjuvant chemotherapy: A multicenter retrospective study
(SAN ANTONIO BREAST CANCER SYMPOSIUM 43rd Annual SABCS 2018)
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オラパリブの乳癌適応拡大に向けた当院の取り組み
(日本人類遺伝学会第63回大会 2018)
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乳癌切除標本における比誘電率計測と非侵襲マイクロ波散乱場断層イメージングに関する研究
(第26回日本乳癌学会学術総会 2018)
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Education (1)：
- - 1987 Wakayama Medical University
Professional career (1)：
- PhD (Wakayama Medical University)
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