Rchr
J-GLOBAL ID：201701010052906420
Update date: Jun. 02, 2024
Mukai Takahito
ムカイ タカヒト | Mukai Takahito
Affiliation and department：
Research field (1)：
Genomics
Research keywords (5)：
tRNA
, Bioinformatics
, non-canonical amino acids
, The genetic code
, Synthetic biology
Research theme for competitive and other funds (6)：
Papers (33)：
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Kyle S Hoffman, Christina Z Chung, Takahito Mukai, Natalie Krahn, Han-Kai Jang, Nileeka Balasuriya, Patrick O'Donoghue, Dieter Söll. Recoding UAG to selenocysteine in Saccharomyces cerevisiae. RNA. 2023. rna.079658.123-rna.079658.123
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Li-Tao Guo, Kazuaki Amikura, Han-Kai Jiang, Takahito Mukai, Xian Fu, Yane-Shih Wang, Patrick O’Donoghue, Dieter Söll, Jeffery M. Tharp. Ancestral Archaea Expanded the Genetic Code with Pyrrolysine. Journal of Biological Chemistry. 2022. 102521-102521
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Hironobu Fujita, Ayane Osaku, Yuto Sakane, Koki Yoshida, Kayoko Yamada, Seia Nara, Takahito Mukai, Masayuki Su’etsugu. Enzymatic Supercoiling of Bacterial Chromosomes Facilitates Genome Manipulation. ACS Synthetic Biology. 2022
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Haolin Zhang, Xuemei Gong, Qianqian Zhao, Takahito Mukai, Oscar Vargas-Rodriguez, Huiming Zhang, Yuxing Zhang, Paul Wassel, Kazuaki Amikura, Julie Maupin-Furlow, et al. The tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNAPyl pairs in the same organism. Nucleic Acids Research. 2022
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Takahito Mukai, Kazuaki Amikura, Xian Fu, Dieter Söll, Ana Crnković. Indirect Routes to Aminoacyl-tRNA: The Diversity of Prokaryotic Cysteine Encoding Systems. Frontiers in Genetics. 2022. 12
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Patents (15)：
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COMPOSITIONS AND METHODS FOR MAKING SELENOCYSTEINE CONTAINING POLYPEPTIDES
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機能性DNAカセット及びプラスミド(申請取り下げ)
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COMPOSITIONS AND METHODS FOR MAKING SELENOCYSTEINE CONTAINING POLYPEPTIDES
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METHOD FOR SYNTHESIS OF SUPPRESSOR tRNA, DNA CONSTRUCT, AND PRODUCTION OF PROTEIN HAVING NON-NATURAL AMINO ACID INTEGRATED THEREIN BY USING THE DNA CONSTRUCT
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Method for constructing recombinant bacterium for producing non-native protein, and utilization of same
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Lectures and oral presentations (12)：
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シンプル ゲノム合成
(第17回日本ゲノム微生物学会年会 2023)
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Designing the central dogma system of zombie cells
(2022)
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Chromosome shuttling between cell-free systems and E. coli cells
(The 3rd International BioDesign Research Conference 2022)
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ゲノムのミライ 作れる細胞の設計
(第16回日本ゲノム微生物学会年会 2022)
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大腸菌ゲノムの分断化とポータブル化
(第17回21世紀大腸菌研究会 2021)
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Education (2)：
- 2006 - 2011 東京大学大学院 理学系研究科 生物化学専攻
- 2002 - 2006 The University of Tokyo
Work history (6)：
Association Membership(s) (2)：
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