Rchr
J-GLOBAL ID:201701010095761077   Update date: Feb. 09, 2024

OHTSUKI Shozo

オオツキ ショウゾウ | OHTSUKI Shozo
Affiliation and department:
Job title: Research Associate (Postdoctoral)
Research field  (4): Nanobioscience ,  Molecular biology ,  Cell biology ,  Immunology
Research keywords  (12): Cell metabolism ,  Vasculitis ,  Immunology ,  Cell Biology ,  Nucleic Acid Drug ,  Protein Engineering ,  Signal Transduction ,  Cytokine Receptor ,  Receptor Signaling ,  Molecular Biology ,  Biopharmaceutics ,  DDS
Papers (20):
  • Huimin Zhang, Hirohisa Okuyama, Abhinav Jain, Rohit R Jadhav, Bowen Wu, Ines Sturmlechner, Jose Morales, Shozo Ohtsuki, Cornelia M Weyand, Jörg J Goronzy. PREX1 improves homeostatic proliferation to maintain a naïve CD4 T cell compartment in older age. JCI insight. 2024
  • Yuki Sato, Abhinav Jain, Shozo Ohtsuki, Hirohisa Okuyama, Ines Sturmlechner, Yoshinori Takashima, Kevin-Phu C. Le, Melanie C. Bois, Gerald J. Berry, Kenneth J. Warrington, et al. Stem-like CD4+ T cells in perivascular tertiary lymphoid structures sustain autoimmune vasculitis. Science Translational Medicine. 2023. 15. 712. 712
  • Shozo Ohtsuki, Chenyao Wang, Ryu Watanabe, Hui Zhang, Mitsuhiro Akiyama, Melanie C Bois, Joseph J Maleszewski, Kenneth J Warrington, Gerald J Berry, Jörg J Goronzy, et al. Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis. Cell Reports Medicine. 2023. 4. 4. 101012-101012
  • Huimin Zhang, Rohit R. Jadhav, Wenqiang Cao, Isabel N. Goronzy, Tuantuan V. Zhao, Jun Jin, Shozo Ohtsuki, Zhaolan Hu, Jose Morales, William J. Greenleaf, et al. Aging-associated HELIOS deficiency in naive CD4+ T cells alters chromatin remodeling and promotes effector cell responses. Nature Immunology. 2022. 24. 1. 96-109
  • Tuantuan V. Zhao, Zhaolan Hu, Shozo Ohtsuki, Ke Jin, Bowen Wu, Gerald J. Berry, Robert L. Frye, Jörg J. Goronzy, Cornelia M. Weyand. Hyperactivity of the CD155 immune checkpoint suppresses anti-viral immunity in patients with coronary artery disease. Nature Cardiovascular Research. 2022. 1. 7. 634-648
more...
Lectures and oral presentations  (13):
  • 免疫細胞へのデリバリーに適したDNAナノ構造体の構造的特徴の解明
    (第68回日本薬学会近畿支部総会・大会 2018)
  • ナノ構造化核酸の免疫細胞による取り込みにおけるマクロファージスカベンジャーレセプター1の寄与
    (第68回 日本薬学会近畿支部総会・大会 2018)
  • 多足型DNA構造体中のCpG motifの位置依存的な生物活性の評価
    (第15回東京理科大学薬学部DDS研究センターシンポジウム 2017)
  • 塩基修飾核酸とナノ構造化の組み合わせによる機能性核酸の活性増強
    (第67回 日本薬学会近畿支部総会・大会 2017)
  • CpG DNAの効率的デリバリーを目的とした疎水性相互作用により形成されるDNA超分子の開発
    (日本核酸医薬学会 第3回年会 2017)
more...
Education (3):
  • 2015 - 2018 Kyoto University Graduate School of Pharmaceutical Sciences Ph.D. Candidate
  • 2013 - 2015 Kyoto University Graduate School of Pharmaceutical Sciences
  • 2009 - 2013 Osaka University of Pharmaceutical Sciences
Professional career (1):
  • PhD (Kyoto University)
Work history (4):
  • 2021/04 - 現在 Mayo Clinic College of Medicine and Science Department of Medicine Research Associate (Postdoctoral)
  • 2020/10 - 2021/04 U.S. Department of Veterans Affairs VA Palo Alto Health Care System Affiliate
  • 2018/10 - 2021/04 Stanford University, School of Medicine Postdoctoral Research Fellow
  • 2018/04 - 2018/09 Kyoto University Graduate School of Pharmaceutical Sciences Research Fellow
Awards (3):
  • 2015/08 - Featured Articles
  • 2014/05 - The Nagai Foundation Tokyo Graduate Student Scholarship 2014
  • 2013/03 - Alumni Association of Osaka University of Pharmaceutical Sciences
Association Membership(s) (2):
National Postdoctoral Association ,  American Association for the Advancement of Science
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