Rchr
J-GLOBAL ID:201701010095761077   Update date: May. 05, 2021

OHTSUKI Shozo

オオツキ ショウゾウ | OHTSUKI Shozo
Affiliation and department:
Job title: Research Associate
Research field  (4): Nanobioscience ,  Molecular biology ,  Cell biology ,  Immunology
Research keywords  (12): Cell metabolism ,  Vasculitis ,  Immunology ,  Nucleic Acid Drug ,  Cell Biology ,  Protein Engineering ,  Signal Transduction ,  Cytokine Receptor ,  Receptor Signaling ,  Molecular Biology ,  Biopharmaceutics ,  DDS
Papers (14):
  • Keisuke Umemura, Shozo Ohtsuki, Makoto Nagaoka, Kosuke Kusamori, Takao Inoue, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa. Critical contribution of macrophage scavenger receptor 1 to the uptake of nanostructured DNA by immune cells. Nanomedicine : nanotechnology, biology, and medicine. 2021. 102386-102386
  • Yuki Araie, Shozo Ohtsuki, Soyoung Park, Makoto Nagaoka, Keisuke Umemura, Hiroshi Sugiyama, Kosuke Kusamori, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa. Combined use of chemically modified nucleobases and nanostructured DNA for enhanced immunostimulatory activity of CpG oligodeoxynucleotide. Bioorganic & medicinal chemistry. 2021. 29. 115864-115864
  • Bowen Wu, Jingtao Qiu, Tuantuan V Zhao, Yanan Wang, Toshihisa Maeda, Isabel N Goronzy, Mitsuhiro Akiyama, Shozo Ohtsuki, Ke Jin, Lu Tian, et al. Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells. Cell metabolism. 2020. 32. 6. 967-980
  • Ricardo A Fernandes, Leon Su, Yoko Nishiga, Junming Ren, Aladdin M Bhuiyan, Ning Cheng, Calvin J Kuo, Lora K Picton, Shozo Ohtsuki, Robbie G Majzner, et al. Immune receptor inhibition through enforced phosphatase recruitment. Nature. 2020. 586. 7831. 779-784
  • Tatsuoki Maezawa, Shozo Ohtsuki, Kumi Hidaka, Hiroshi Sugiyama, Masayuki Endo, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa. DNA density-dependent uptake of DNA origami-based two-or three-dimensional nanostructures by immune cells. Nanoscale. 2020. 12. 27. 14818-14824
more...
Lectures and oral presentations  (13):
  • 免疫細胞へのデリバリーに適したDNAナノ構造体の構造的特徴の解明
    (第68回日本薬学会近畿支部総会・大会 2018)
  • ナノ構造化核酸の免疫細胞による取り込みにおけるマクロファージスカベンジャーレセプター1の寄与
    (第68回 日本薬学会近畿支部総会・大会 2018)
  • 多足型DNA構造体中のCpG motifの位置依存的な生物活性の評価
    (第15回東京理科大学薬学部DDS研究センターシンポジウム 2017)
  • 塩基修飾核酸とナノ構造化の組み合わせによる機能性核酸の活性増強
    (第67回 日本薬学会近畿支部総会・大会 2017)
  • CpG DNAの効率的デリバリーを目的とした疎水性相互作用により形成されるDNA超分子の開発
    (日本核酸医薬学会 第3回年会 2017)
more...
Education (3):
  • 2015 - 2018 Kyoto University Ph.D. Candidate
  • 2013 - 2015 Kyoto University
  • 2009 - 2013 Osaka University of Pharmaceutical Sciences
Professional career (1):
  • PhD (Kyoto University)
Work history (3):
  • 2021/04 - 現在 Mayo Clinic Research Associate
  • 2018/10 - 2021/04 Stanford University, School of Medicine Postdoctoral Research Fellow
  • 2018/04 - 2018/09 Kyoto University Graduate School of Pharmaceutical Sciences Research Fellow
Awards (3):
  • 2015/08 - Featured Articles
  • 2014/05 - The Nagai Foundation Tokyo Graduate Student Scholarship 2014
  • 2013/03 - Alumni Association of Osaka University of Pharmaceutical Sciences
Association Membership(s) (2):
National Postdoctoral Association ,  American Association for the Advancement of Science
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