Zhen Chen

チンシン | Zhen Chen

Affiliation and department：
Job title：講師

Research field (3)： Nutrition and health science , Metabolism and endocrinology , Food sciences

Research keywords (6)： food chemistry , LC/MS , plasmalogen , mitochondria , lipidomics , lipid peroxide

Research theme for competitive and other funds (3)：

2022 - 2025 筋腎連関によるビタミンKのミトコンドリアを標的とした新規作用
2019 - 2021 Studies on the association of lipid hydroperoxides and Alzheimer's disease by LC/MS
2019 - 2020 Comparative studies on choline and ethanolamine plasmalogen molecular species for their cytoprotective and anti-lipid oxidative effects

Papers (71)：

呉訓智, 何欣蓉, 江口美祈, 陳震, 千葉仁志, 惠淑萍. フラジンはミトコンドリア動態の改善を介して酸化ストレスからヒト腎臓細胞を保護する(Flazin protects human kidney cells against oxidative stress via improving mitochondrial dynamics.). 日本未病学会学術総会抄録集. 2023. 30回. 49-49
呉訓智, 何欣蓉, 陳震, 陳一凡, 沈テン秋, 千葉仁志, 惠淑萍. フラジンはヒト尿細管HK-2細胞における脂肪酸を介した脂質毒性を抑制する(Flazin attenuates fatty acid mediated lipotoxicity in human tubular HK-2 cells). 日本栄養・食糧学会大会講演要旨集. 2023. 77回. 173-173
Zhen Chen, Nianqiu Shen, Xunzhi Wu, Jiaping Jia, Yue Wu, Hitoshi Chiba, Shuping Hui. Extraction and Quantitation of Phytosterols from Edible Brown Seaweeds: Optimization, Validation, and Application. Foods (Basel, Switzerland). 2023. 12. 2
Zhen Chen, Shuji Sai, Kiyoshi Nagumo, Yue Wu, Hitoshi Chiba, Shu-Ping Hui. Distinctive serum lipidomic profile of IVIG-resistant Kawasaki disease children before and after treatment. PloS one. 2023. 18. 3. e0283710
Chen Zhen, Wu Xunzhi, Chiba Hitoshi, Hui Shu-Ping. オミックス技術による酸化脂質の研究質量分析法を用いた生物学的応用においての酸化リピドミクス(Investigating oxidized lipids in an omics way: Oxidative lipidomics in biological applications using mass spectrometry). Medical Mass Spectrometry. 2022. 6. 2. 72-84

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MISC (67)：

櫻井俊宏, 陳震, 茂木すみれ, 千葉仁志, 惠淑萍. 培養肝細胞から放出されるLDLの脂質プロフィール解析. 臨床化学(Web). 2023. 52
川上志野, 川上憲太郎, GOWDA Siddabasave Gowda B., CHEN Zhen, 吹谷智, LIANG Chongsheng, HAI Han, 石塚敏, 小椋義俊, 後藤恭宏, et al. 高脂肪食摂取ラット盲腸で増加した遊離脂肪酸種が腸内細菌に与える影響の評価. 日本農芸化学会北海道支部学術講演会講演要旨集(Web). 2023. 2023
櫻井俊宏, 三浦佑介, 高田康徳, GOWDA Divyavani, 陳震, 関島将人, 千葉仁志, 惠淑萍. 尿中コレステリルエステルと腎障害の関連. JSBMS Letters. 2022. 47. 2
川上憲太郎, GOWDA Siddabasave Gowda B., CHEN Zhen, 吹谷智, LIANG Chongsheng, HAI Han, 石塚敏, 小椋義俊, 後藤恭宏, 前田智也, et al. Elucidation of the effects of the fatty acid profile changes on the gut microbiota composition in the cecum of rats fed a high-fat diet: validation of a fatty-acid hypothesis. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
沈てん秋, 陳震, WU Yue, 呉訓智, 千葉仁志, 惠淑萍. Optimization of extraction methods for seaweed phytosterols and evaluation of their neurological bioactivity. 臨床化学(Web). 2022. 51

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Lectures and oral presentations (1)：

Plasmalogens as dietary functional phospholipids: beneficial functions and amount variation as food ingredient
(The 6th Hokkaido University Cross-Departmental Symposium 2020)

Professional career (1)：

Work history (3)：

2020/10 - 現在北海道大学大学院保健科学研究院講師
2017/04 - 2020/09 Hokkaido University Faculty of Health Sciences Assistant professor
2016/07 - 2017/03 Hokkaido University Faculty of Health Sciences Postdoc

Awards (3)：

2020/09 - Japan Society of Clinical Chemistry Hokkaido Branch Excellent Abstract Award
2019/10 - Japan Society of Clinical Chemistry Hokkaido Branch Award
2018/09 - Japanese Society for Biomedical Mass Spectrometry Excellent Poster Award for Young Investigators The 43rd Annual Meeting of the Japanese Society for Biomedical Mass Spectrometry

Association Membership(s) (3)：

Japan Society for Lipid Hydroperoxide Biology and Medicine , JAPANESE SOCIETY FOR BIOMEDICAL MASS SPECTROMETRY , JAPAN SOCIETY OF CLINICAL CHEMISTRY

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