Rchr
J-GLOBAL ID:201701010204079354   Update date: Apr. 22, 2021

Zhen Chen

チン シン | Zhen Chen
Affiliation and department:
Job title: 講師
Research field  (3): Nutrition and health science ,  Metabolism and endocrinology ,  Food sciences
Research keywords  (6): food chemistry ,  LC/MS ,  plasmalogen ,  mitochondria ,  lipidomics ,  lipid peroxide
Research theme for competitive and other funds  (2):
  • 2019 - 2021 Studies on the association of lipid hydroperoxides and Alzheimer's disease by LC/MS
  • 2019 - 2020 Comparative studies on choline and ethanolamine plasmalogen molecular species for their cytoprotective and anti-lipid oxidative effects
Papers (33):
  • Rojeet Shrestha, Zhen Chen, Zijun Gao, Yifan Chen, Emiko Okada, Shigekazu Ukawa, Takafumi Nakagawa, Koshi Nakamura, Akiko Tamakoshi, Hitoshi Chiba, et al. HPLC with spectrophotometric or mass spectrometric detection for quantifying very-long chain fatty acids in human plasma and its association with cardiac risk factors. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 2021. 000456322110071-000456322110071
  • Yasuyuki Tamai, Zhen Chen, Yue Wu, Jun Okabe, Yoshinao Kobayashi, Hitoshi Chiba, Shu-Ping Hui, Akiko Eguchi, Motoh Iwasa, Masaaki Ito, et al. Branched-chain amino acids and l-carnitine attenuate lipotoxic hepatocellular damage in rat cirrhotic liver. Biomedicine & Pharmacotherapy. 2021. 135. 111181-111181
  • Toshihiro Sakurai, Zhen Chen, Arisa Yamahata, Takahiro Hayasaka, Hiroshi Satoh, Hirotaka Sekiguchi, Hitoshi Chiba, Shu-Ping Hui. A mouse model of short-term, diet-induced fatty liver with abnormal cardiolipin remodeling via downregulated Tafazzin gene expression. Journal of the Science of Food and Agriculture. 2021
  • Yue Wu, Zhen Chen, Jiaping Jia, Hitoshi Chiba, Shu-Ping Hui. Quantitative and Comparative Investigation of Plasmalogen Species in Daily Foodstuffs. Foods. 2021. 10. 1. 124-124
  • Chen, Zhen, Liang, Qiangrong, Wu, Yue, Gao, Zijun, Kobayashi, Satoru, Patel, Joy, Li, Cairong, Cai, Fei, Zhang, Youhua, Liang, Chongsheng, et al. Comprehensive lipidomic profiling in serum and multiple tissues from a mouse model of diabetes. Metabolomics. 2020. 16. 11. 115-115
more...
MISC (52):
  • 上野 朱音, 櫻井 俊宏, 関島 将人, 山端 ありさ, 陳 震, 千葉 仁志, 惠 淑萍. 酸化HDLにより誘導された肝細胞過酸化脂質プロフィールの変動. 臨床化学. 2020. 49. Suppl.1. 151-151
  • 山本 祐輔, 櫻井 俊宏, 陳 震, Wu Yue, 藤井 佑樹, 能祖 一裕, 千葉 仁志, 惠 淑萍. 健常者及び非アルコール性脂肪性肝疾患患者の血清中LysoPEプロファイル. 臨床化学. 2020. 49. Suppl.1. 213-213
  • Wu Yue, 陳 震, 千葉 仁志, 惠 淑萍. エーテル結合型リン脂質は、Keap1-Nrf2を介した酸化損傷から肝細胞を保護する(Ether-linked phospholipids protect hepatocytes from oxidative damage via Keap1-Nrf2 pathway). 臨床化学. 2020. 49. Suppl.1. 215-215
  • 陳 震, 齋 秀二, Wu Yue, 千葉 仁志, 惠 淑萍. IVIG感受性川崎病患児と抵抗性患児との間にみられる脂質の特徴の違い(Differential lipid characteristics in Kawasaki disease between IVIG sensitive and resistant children). 臨床化学. 2020. 49. Suppl.1. 215-215
  • 惠 淑萍, 陳 震, Liang Qiangrong, Wu Yue, 高 紫君, 梁 崇晟, 千葉 仁志. LC/HR-MS/MSによる、2型糖尿病マウスの血清と組織におけるリピドームプロファイルの変化(Lipidomic profile variation in serum and tissues from type 2 diabetic mice by LC/HR-MS/MS). 臨床化学. 2020. 49. Suppl.1. 218-218
more...
Lectures and oral presentations  (1):
  • Plasmalogens as dietary functional phospholipids: beneficial functions and amount variation as food ingredient
    (The 6th Hokkaido University Cross-Departmental Symposium 2020)
Professional career (1):
  • Doctor (Ocean University of China)
Work history (3):
  • 2020/10 - 現在 北海道大学 大学院保健科学研究院 講師
  • 2017/04 - 2020/09 Hokkaido University Faculty of Health Sciences Assistant professor
  • 2016/07 - 2017/03 Hokkaido University Faculty of Health Sciences Postdoc
Awards (3):
  • 2020/09 - Japan Society of Clinical Chemistry Hokkaido Branch Excellent Abstract Award
  • 2019/10 - Japan Society of Clinical Chemistry Hokkaido Branch Award
  • 2018/09 - Japanese Society for Biomedical Mass Spectrometry Excellent Poster Award for Young Investigators The 43rd Annual Meeting of the Japanese Society for Biomedical Mass Spectrometry
Association Membership(s) (3):
Japan Society for Lipid Hydroperoxide Biology and Medicine ,  JAPANESE SOCIETY FOR BIOMEDICAL MASS SPECTROMETRY ,  JAPAN SOCIETY OF CLINICAL CHEMISTRY
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