Kawaguchi Mitsuyasu

カワグチミツヤス | Kawaguchi Mitsuyasu

Affiliation and department：
Homepage URL (1)： http://www.phar.nagoya-cu.ac.jp/hp/ykg/Yakka/index.html

Research field (2)： Chemical biology , Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (7)：

2022 - 2025 SIRT脱ミリストイル化活性選択的阻害剤の開発と細胞機能の光操作
2021 - 2023 プロテアソーム分解過程可視化蛍光プローブの開発と新規プロテアソーム阻害剤の探索
2019 - 2023 Fluorescent imaging probes for epigenetic enzymes with specialized amino acids
2018 - 2020 Development of molecular-targeting prodrug for ENPP1
2016 - 2018 New fluorescence NO probe adopting radical-specific reactivity

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Papers (47)：

Mitsuyasu Kawaguchi, Shohei Minami, Naoya Ieda, Hidehiko Nakagawa. [1,2,4]Triazolo[1,5-a]pyrimidine derivatives: Structure-activity relationship study leading to highly selective ENPP1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 2024. 110. 129820-129820
Naoya Ieda, Akira Nakamura, Natsumi Tomita, Kei Ohkubo, Ryo Izumi, Yuji Hotta, Mitsuyasu Kawaguchi, Kazunori Kimura, Hidehiko Nakagawa. A BODIPY-picolinium-cation conjugate as a blue-light-responsive caged group. RSC Advances. 2023. 13. 26375-26379
Naoya Ieda, Mitsuyasu Kawaguchi, Hidehiko Nakagawa. Substituent Effects at the <i>N</i>-Nitrosoaminophenol Moiety of a Photoinduced-Electron-Transfer-Driven Nitric Oxide Releaser. Chemical and Pharmaceutical Bulletin. 2023. 71. 6. 447-450
Naoya Ieda, Masato Sawada, Runa Oguchi, Masato Itoh, Seina Hirakata, Daisuke Saitoh, Akito Nakao, Mitsuyasu Kawaguchi, Kazunobu Sawamoto, Toshitada Yoshihara, et al. An Optochemical Oxygen Scavenger Enabling Spatiotemporal Control of Hypoxia. Angewandte Chemie International Edition. 2023. 62. 20
Daisuke Saitoh, Ayumi Suzuki, Naoya Ieda, Zuoyue Liu, Yasuko Osakada, Mamoru Fujitsuka, Mitsuyasu Kawaguchi, Hidehiko Nakagawa. Photoinduced NO-Release from Polymer Dots Doped with an Ir(III) Complex and N-Methyl-N-nitroso-4-aminophenol. Organic & Biomolecular Chemistry. 2023

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MISC (2)：

石谷隆一郎, 川口充康, 岡部隆義, 奥平真一, 西増弘志, 小島宏建, 濡木理, 青木淳賢, 長野哲雄. 翻訳後修飾に着目したシグナル伝達研究と創薬の最前線シグナル伝達にかかわる因子Autotaxinの構造ベース創薬. 日本薬学会年会要旨集. 2014. 134年会. 1. 255-255
川口充康, 岡部隆義, 寺井琢也, 藤川雄太, 青木淳賢, 小島宏建, 長野哲雄. 新規NPP6活性検出蛍光プローブの開発と阻害剤スクリーニング. 日本薬学会年会要旨集. 2010. 130年会. 2. 114-114

Patents (6)：

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Books (2)：

Lectures and oral presentations (2)：

Education (2)：

Professional career (1)：

Work history (6)：

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Association Membership(s) (3)：

日本ケミカルバイオロジー学会 , 日本化学会 , 日本薬学会

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