Rchr
J-GLOBAL ID：201701012551459879   Update date: Oct. 09, 2024

Inaba Hironori

イナバ ヒロノリ | Inaba Hironori
Homepage URL  (1)： https://www.medic.mie-u.ac.jp/organization/course/kaibo/
Research field  (2)： Anatomy ,  Cell biology
Research keywords  (4)： primary cilia ,  クライオ電子線トモグラフィー ,  光遺伝学 ,  細胞生物学
Research theme for competitive and other funds  (5)：
  • 2022 - 2025 Analyses on RhoA-induced intracellular calcium signaling using optogenetics
  • 2022 - PLCepsilonが担う持続的なCa2+シグナルの一次線毛退縮における機能の解明
  • 2018 - 2019 RAC1光スイッチによるアクチン重合・分岐の急速凍結クライオ電子線トモグラフィー
  • 2018 - 2019 シグナル分子の光操作による上皮細胞集団遊走機構の解析
  • ホスホリパーゼCεによる一次線毛退縮制御機構の解明
Papers (8)：
  • Hironori Inaba, Tsuyoshi Imasaki, Kazuhiro Aoyama, Shogo Yoshihara, Hiroko Takazaki, Takayuki Kato, Hidemasa Goto, Kaoru Mitsuoka, Ryo Nitta, Takao Nakata. Cryo-electron tomography of the actin cytoskeleton and membrane organization during lamellipodia formation using optogenetics. 2024
  • Hiroshi Hanafusa, Shin Kedashiro, Mako Gotoh, Ko-Hei Saitoh, Hironori Inaba, Tomoki Nishioka, Kozo Kaibuchi, Masaki Inagaki, Naoki Hisamoto, Kunihiro Matsumoto. LRRK1-mediated NDEL1 phosphorylation promotes cilia disassembly via dynein-2-driven retrograde intraflagellar transport. Journal of cell science. 2022. 135. 21
  • Hironori Inaba, Qianqian Miao, Takao Nakata. Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling. Journal of Biological Chemistry. 2021. 296. 100290-100290
  • Takanobu Shimizu, Takeshi Nakamura, Hironori Inaba, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Takao Nakata, Hiroshi Nishina, Yutaka Hata. The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation. The Journal of biological chemistry. 2020. 295. 32. 11214-11230
  • Hironori Inaba, Daishi Yamakawa, Yasuko Tomono, Atsushi Enomoto, Shinji Mii, Kousuke Kasahara, Hidemasa Goto, Masaki Inagaki. Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase. Biochemical and Biophysical Research Communications. 2018. 498. 3. 544-550
ｍore...
MISC (2)：
  • Optogenetic manipulations of small GTPases and observations of their intracellular functions. 2021. 56. 2. 59-63
  • Hidemasa Goto, Hironori Inaba, Masaki Inagaki. Mechanisms of ciliogenesis suppression in dividing cells. Cell. Mol. Life Sci. 2017. 74. 5. 881-890
Books (1)：
  • Encyclopedia of Signaling Molecule 2nd edition
    Springer 2018 ISBN:9783319671994
Lectures and oral presentations  (22)：
  • 低分子量Gタンパク質の光遺伝学的制御により明らかとなったRhoAによる細胞内カルシウムシグナル制 御
    (第126回日本解剖学会総会・全国学術集会 / 第98回日本生理学会大会 合同大会 2021)
  • Optogenetic control of small GTPases reveals RhoA-mediated intracellular calcium signaling
    (Cell Bio Virtual 2020 - An Online ASCB/EMBO Meeting 2020)
  • Analyses of the regulation of PLCε activity by small GTPases using optogenetics
    (The 72nd Annual Meeting of the Japan Society for Cell Biology 2020)
  • Analyses on the intracellular Ca2+ signaling regulated by RhoA using optogen etics
    (Joint Annual Meeting of 71st JSCB & 19th PSSJ 2019)
  • CDK1によるケラチン5のリン酸化が皮膚基底層上皮細胞の細胞分裂に必要である
    (日本細胞生物学会大会講演要旨集 2017)
ｍore...
Education (2)：
  • 2008 - 2013 The University of Tokyo
  • 2004 - 2008 The University of Tokyo Faculty of Agriculture
Professional career (1)：
  • 博士(農学)
Work history (3)：
  • 2022/03 - 現在 Mie University Graduate School of Medicine, Department of Histology and Cell Biology Lecturer
  • 2017/01 - 2022/02 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Matrix Cell Biology Assistant Professor
  • 2013/04/01 - 2016/12/31 Aichi Cancer Center Research Institute Division of Biochemistry Research resident
Awards (2)：
  • 2017/08 - 平成29年度学長裁量優秀若手研究者奨励賞(稲葉弘哲)
  • 2017/02 - 東京医科歯科大学脳統合機能研究センター 第9回CBIR+ONSA共催若手インスパイアシンポジウム優秀賞(稲葉弘哲)
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