Ieda Naoya

Homepage URL (2)： https://www.pharm.hokudai.ac.jp/bunseki/index.html , https://www.pharm.hokudai.ac.jp/bunseki/en/index.html

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (5)： caged compound , Nitric oxide , ケミカルバイオロジー , 合成化学 , 光化学

Research theme for competitive and other funds (20)：

2023 - 2024 オルガネラから動物個体まで応用可能な光酸素スカベンジャーの開発
2021 - 2024 Application of light-controllable nitric oxide donor for lower urinary tract symptom
2020 - 2023 体外から制御可能な低エネルギー光ケージド化合物群の開発
2020 - 2023 光制御可能なNOドナー「NORD-1」の難治性EDへの応用
2019 - 2023 Fluorescent imaging probes for epigenetic enzymes with specialized amino acids

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Papers (55)：

Naoya Ieda, Hideo Takakura, Hirotaka Maeta, Takayuki Ohira, Koki Tsuchiya, Kohei Nakajima, Mikako Ogawa. Investigation of the substituent effect of indocyanine green derivatives for lymph imaging. Bioorganic Medicinal Chemistry. 2024. 117824-117824
Mitsuyasu Kawaguchi, Shohei Minami, Naoya Ieda, Hidehiko Nakagawa. [1,2,4]Triazolo[1,5-a]pyrimidine derivatives: Structure-activity relationship study leading to highly selective ENPP1 inhibitors. Bioorganic Medicinal Chemistry Letters. 2024. 110. 129820-129820
Koki Tsuchiya, Hideo Takakura, Kohei Nakajima, Naoya Ieda, Takashi Kaneko, Takeshi Hirasawa, Masato Kobayashi, Yoshihisa Yamaoka, Miya Ishihara, Tetsuya Taketsugu, et al. Piperazine based pH-responsive cyanine dyes for cancer cell photoacoustic imaging. Journal of Photochemistry and Photobiology A: Chemistry. 2024. 453. 115634-115634
Yuji Hotta, Kyoya Oyama, Takuma Yoshida, Naoya Ieda, Taiki Mori, Yasuhiro Horita, Tomoya Kataoka, Yoko Furukawa-Hibi, Susumu Ohya, Hidehiko Nakagawa, et al. The Effects of a Red-Light Controllable Nitric Oxide Donor, NORD-1, on Erectile Dysfunction in Rats with Streptozotocin Induced Diabetes Mellitus. The World Journal of Men's Health. 2024. 42. e58
Koki Ogawara, Osamu Inanami, Hideo Takakura, Kenichiro Saita, Kohei Nakajima, Sonu Kumar, Naoya Ieda, Masato Kobayashi, Tetsuya Taketsugu, Mikako Ogawa. Theoretical Design and Synthesis of Caged Compounds Using X-Ray-Triggered Azo Bond Cleavage. Advanced Science. 2024. 11. 12

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MISC (7)：

山口遥己, 川口充康, 井田智章, 松永哲郎, 家田直弥, 赤池孝章, 中川秀彦. S-sulfhydryl化タンパク質解析を志向したhydropersulfideラベル化蛍光プローブの開発. 日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会講演要旨集. 2021. 2021
川口充康, HAN Xiang, 家田直弥, 可野邦行, 青木淳賢, 中川秀彦. ENPP1活性検出蛍光プローブの開発とケミカルスクリーニング. メディシナルケミストリーシンポジウム講演要旨集. 2017. 35th. 98
Hidehiko Nakagawa, Naoki Fukushima, Naoya Ieda, Takayoshi Suzuki, Naoki Miyata. Photo-inducible hydrogen sulfide releaser using ketoprofenate photocages. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2014. 39. S5-S5
Naoya Ieda, Yuji Hotta, Kazunori Kimura, Naoki Miyata, Hidehiko Nakagawa. Photo-manipulation of vasodilation with a novel photo-controllable nitric oxide releaser based on N-nitrosoaminophenol. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2014. 39. S48-S48
家田直弥, 中川秀彦, 中川秀彦, 堀之内妙子, PENG Tao, YANG Dan, 津元裕樹, 鈴木孝禎, 福原潔, 宮田直樹, et al. Nitrobenzene構造を有する光応答性ONOO^-ドナーの創製. 酸化反応討論会講演要旨集. 2011. 44th

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Patents (8)：

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Lectures and oral presentations (7)：

ケージドNOを駆使した哺乳動物での血管の光操作
(日本薬学会第144年会 2024)
光制御分子を駆使した生体内ガス状分子の機能操作
(第19回ABC-InFO講演会 2023)
光血管拡張剤を駆使した動物個体における血流の光制御
(第96回日本生化学会大会 2023)
低酸素を操る光酸素スカベンジャーの開発と鉄含有タンパク質の光操作
(メタルバイオサイエンス研究会2023 2023)
光誘起電子移動駆動型ケージド分子群の開発と生体機能の光制御
(第61回電子スピンサイエンス学会年会 2022)

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Education (3)：

2010 - 2012 Nagoya City University
2008 - 2010 Nagoya City University
2004 - 2008 Meijo University Faculty of Pharmacy Department of Pharmacy

Professional career (1)：

博士(薬学) (名古屋市立大学)

Work history (6)：

2023/06 - 現在名古屋市立大学大学院薬学研究科客員准教授(兼任)
2023/06 - 現在 Hokkaido University Graduate School of Pharmaceutical Sciences Associate Professor
2021/01 - 2023/05 Nagoya City University Graduate School of Pharmaceutical Sciences Department of Organic and Medicinal Chemistry Assistant Professor
2012/07 - 2020/12 Nagoya City University Graduate School of Pharmaceutical Sciences, Department of Organic and Medicinal Chemistry Research Associate
2016/04 - 2017/03 University of Pennsylvania Department of Chemistry Visiting Scholar

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Committee career (1)：

2024/04 - 現在ファルマシアトピックス小委員

Awards (5)：

2018/11 - ICPAC Langkawi Lecture Award
2013/06 - 第64回日本酸化ストレス学会優秀演題賞
2012/10 - 第3回大津会議修了
2012 - Sasakawa Scientific Research Grant Encouraging Prize
2010/07 - The 66th Meeting of Society for Free Radical Research Japan Scholarly Encouraging Prize

Association Membership(s) (6)：

The Japanese Photochemistry Association , The Society of Synthetic Organic Chemistry, Japan , Society for Free Radical Research Japan , The Pharmaceutical Society of Japan , 日本ケミカルバイオロジー学会 , The Chemical Society of Japan

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