2018 - 2021 Search for seeds of anti-lifestyle-related disease drugs and antineoplastic drugs from invasive alien species
2017 - 2021 Search for new natural products with anticancer potential in targeting with AMPK, and their combination effects with metformin
2016 - 2019 Research on steroidal glycosides with anti-metabolic syndrome activity in vivo
2013 - 2017 Antitumor natural products targeting PPAR-gamma and their combination effect with clinically used anticancer agents
2009 - 2012 Research on natural products with autophagy-dependent anti-tumoractivity
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Papers (37):
Yukiko Matsuo, Takuya Fujii, Hironao Kato, Kazuki Tomizawa, Haruhiko Fukaya, Katsunori Miyake, Minpei Kuroda, Yoshihiro Mimaki. Lanceolanone A, a new biflavanone, and a chalcone glucoside from the flower heads of Coreopsis lanceolata and their aldose reductase inhibitory activity and AMPK activation. Journal of natural medicines. 2022
Naoko Kuwabara, Yukiko Matsuo, Tsuyoshi Ueki, Yuki Nakamura, Nanami Kase, Taisuke, Okayasu, Yoshihiro Mimaki, Eiichi Tachikawa, Shinji Sato, et al. Inhibitory Effect of Rhei Rhizoma Constituents on the Cortisol Production in ACTH-Stimulated Bovine Adrenal Fasciculata Cells. Traditional Medicine. 2022. 3. 2. 1-7
Yukiko Matsuo, Hiroko Tsuchihashi, Kazuhiro Takatori, Haruhiko Fukaya, Minpei Kuroda, Yoshihiro Mimaki. Cytotoxic triterpene and steroidal glycosides from the seeds of Digitalis purpurea and the synergistic cytotoxicity of steroidal glycosides and etoposide in SBC-3 cells. Bioorganic chemistry. 2022. 122. 105697-105697
Kazuhiro Takatori, Minpei Kuroda, Masaki Mishima, Yukiko Matsuo, Yoshihiro Mimaki. Digipregnosides A-C, three novel rearranged 11,12-secopregnane glycosides, and digipregnosides D and E, 12,20-epoxypregnane glycosides from the seeds of Digitalis purpurea. Tetrahedron Letters. 2021. 70. 153020-153020
松尾侑希子, 井口巴樹, 黒田明平, 三宅克典, 加藤宏直, 木村優花, 三巻祥浩. Triterpene Glycosides from the Underground Parts of Alternanthera philoxeroides Designated as an Invasive Alien Species and Their Cytotoxicity. 生薬学雑誌. 2024. 78. 1
MEDICAL AND PHARMACEUTICAL SOCIETY FOR WAKAN-YAKU
, THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER
, THE JAPANESE SOCIETY OF PHARMACOGNOSY
, THE PHARMACEUTICAL SOCIETY OF JAPAN