Research theme for competitive and other funds (39):
2022 - 2026 糖鎖異常に起因する幹細胞老化プロセスの理解と制御
2023 - 2025 皮膚幹細胞の糖鎖をターゲットとした老化制御に向けての基盤研究
2023 - 2024 Mechanism of epidermal stem cell formation mediated by commensal bacteria
2021 - 2024 組織の凹凸を保持した三次元皮膚モデルの構築と評価指標の確立
2021 - 2024 皮膚老化に伴う組織幹細胞ダイバーシティ破綻機構の解明
2020 - 2024 上皮幹細胞コンパートメントを規定する分子機構と生物学的意義の解明
2023 - 2024 表皮幹細胞ダイナミクスから紐解く皮膚再生と老化
2022 - 2023 Defining mechanobiological effects on epidermal stem cell aging using skin on a chip model
2021 - 2022 加齢皮膚の幹細胞で見られる特徴的糖鎖の機能解析
2021 - 2022 表皮再生と老化を担うタンパク質糖鎖修飾ダイナミクスの解明
2021 - 2022 凹凸構造を保持した三次元皮膚再生に向けての基盤研究
2021 - 2022 表皮幹細胞老化に伴うグライコームシフト:生物学的意義と分子基盤の解明
2020 - 2022 皮膚幹細胞の糖鎖をターゲットとした老化制御に向けての基盤研究
2018 - 2022 Elucidating the cellular and molecular mechanisms of epithelial stem cell aging
2020 - 2021 Elucidating the roles of cell surface glycans on skin stem cell aging
2018 - 2021 Bioengineering of stem cell niche
2020 - 2021 Elucidating the Cellular and Molecular Mechanisms of Stem Cell Aging
2020 - 2021 The roles of ECM protein Fibulin-7 in epidermal stem cell aging
2019 - 2020 Stem cell dynamics on the ocular surface epithelium
2019 - 2020 Identification of lectin biomarkers to define dynamic glycan alterations during epidermal stem cell aging
2019 - 2020 Elucidating the roles of glycosylation during epidermal stem cell aging
2019 - 2020 Stem cell dynamics in pregnant skin
2019 - 2020 Identification of metabolic factors regulating stem cell aging using the African tur-quoise killifish
2018 - 2020 Oral epithelial stem cells: cellular dynamics and future use in regenerative therapy
2017 - 2020 Contribution of distinct cell populations during vascular remodeling
2018 - 2019 Mechanisms of epithelial stem cell aging: implication for future treatments of age-related disorders
2018 - 2019 Identification of lectin biomarkers for aged epidermal stem cells
2018 - 2019 Comprehensive glycome profiling of skin stem cells during aging
2018 - 2019 Identification of lectin biomarkers for aged epidermal stem cells
2017 - 2019 Stem cell aging in the skin epidermis: If stem cells divide more, do they age more?
2017 - 2018 Stem cell dynamics in pregnant skin
2017 - 2018 Stem cell aging in the skin epidermis
2017 - 2018 Mechanisms of stem cell aging in the skin epidermis
2017 - 2018 Stem cell aging in the skin epidermis
2016 - 2018 Epidermal stem cells: from homeostasis to aging
2016 - 2017 Elucidating the mechanisms of vascular remodeling: Search for putative stem/progenitor cells residing in adult vessels
2016 - 2017 Stem cell aging in the skin epidermis
2016 - 2017 Stem cell aging in the skin epidermis
2008 - 2010 精原幹細胞の維持と分化におけるNanos2の機能解析
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Papers (20):
Erna Raja, Gopakumar Changarathil, Lalhaba Oinam, Jun Tsunezumi, Yen Xuan Ngo, Ryutaro Ishii, Takako Sasaki, Kyoko Imanaka-Yoshida, Hiromi Yanagisawa, Aiko Sada. The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging. EMBO reports. 2022
Yen Xuan Ngo, Kenta Haga, Ayako Suzuki, Hiroko Kato, Hiromi Yanagisawa, Kenji Izumi, Aiko Sada. Isolation and Culture of Primary Oral Keratinocytes from the Adult Mouse Palate. Journal of visualized experiments : JoVE. 2021. 175
Kenichi Kimura, Karina Ramirez, Tram Anh Vu Nguyen, Yoshito Yamashiro, Aiko Sada, Hiromi Yanagisawa. Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels. Scientific Reports. 2021. 11. 1
R. Ichijo, M. Kabata, H. Kidoya, F. Muramatsu, R. Ishibashi, K. Abe, K. Tsutsui, H. Kubo, Y. Iizuka, S. Kitano, et al. Vasculature-driven stem cell population coordinates tissue scaling in dynamic organs. Science Advances. 2021. 7. 7. eabd2575-eabd2575
Ryutaro Ishii, Hiromi Yanagisawa, Aiko Sada. Defining compartmentalized stem cell populations with distinct cell division dynamics in the ocular surface epithelium. Development. 2020. 147. 24. dev197590-dev197590
2006 - 2011 The Graduate University for Advanced Studies (SOKENDAI) Department of Genetics School of Life Science
2002 - 2006 Shizuoka University Department of Biology Faculty of Science
Professional career (1):
Doctor of Philosophy (Ph.D) (The Graduate University for Advanced Studies (SOKENDAI))
Work history (9):
2023/07 - 現在 Kyushu University Medical Institute of Bioregulation Professor
2023/07 - 2024/03 Kumamoto University International Research Center for Medical Sciences Professor
2019/10 - 2023/06 Kumamoto University International Research Center for Medical Sciences (IRCMS) Associate Professor
2019/10 - 2023/03 University of Tsukuba Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA) Visiting Associate Professor
2016/04 - 2019/09 University of Tsukuba Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA) Assistant Professor
2014/04 - 2016/03 Japan Society for the Promotion of Science (JSPS) Postdoctoral Fellowship for research abroad
2011/04 - 2016/03 Cornell University Department of Molecular Biology and Genetics Postdoctoral fellow
2011/04 - 2014/03 Human Frontier Science Program (HFSP) Long-Term Fellowship
2008/04 - 2011/03 Japan Society for the Promotion of Science (JSPS) Research Fellowships for doctoral course students (DC1)
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Committee career (16):
2023/04 - 現在 日本再生医療学会 国際委員会
2023/04 - 現在 日本研究皮膚科学会 若手理事
2023/01 - 現在 日本分子生物学会 キャリアパス委員会
2022/11 - 現在 Kumadai-Hub 広報委員
2022/08 - 現在 NPO corporation, Cheiron-Initiative Board member
2022/06 - 現在 The Japanese Society for Investigative Dermatology Diversity Committee
2022/01 - 現在 The International Society of Regenerative Biology(ISRB) Webinar Committee
2011/04 - Human Frontier Science Program (HFSP) Long-term felliowship
2011/03 - 平成23年度総合研究大学院大学研究賞
2010/04 - 平成22年度総合研究大学院大学学長賞
2008/04 - 日本学術振興会 特別研究員(DC1)
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Association Membership(s) (6):
日本再生医療学会
, The International Society of Regenerative Biology(ISRB)
, The Japanese Society for Investigative Dermatology
, Japanese Society of Developmental Biologists
, The Molecular Biology Society of Japan
, The Japanese Biochemical Society