Rchr
J-GLOBAL ID：201701017108218380
Update date: Aug. 26, 2024
Mabashi-Asazuma Hideaki
マバシ ヒデアキ | Mabashi-Asazuma Hideaki
Affiliation and department：
Job title：
Researcher
Homepage URL (2)：
https://bitbiome.co.jp/
,
https://bitbiome.bio/
Research field (1)：
Applied molecular and cellular biology
Research keywords (6)：
Enzyme engineering
, Genome editing
, Cell Engineering
, Glycoengineering
, baculovirus
, insect cells
Research theme for competitive and other funds (3)：
- 2021 - 2025 筋内脂質に着目したサルコペニア発症機構の解明と新たな栄養食事療法の創出
- 2018 - 2021 Rapid large scale VLP vaccine production by genome edited insect cells
- 2018 - 2019 BacBomb: Targeting antibody drug delivery system using baculovirus
Papers (22)：
-
Hideaki Mabashi-Asazuma, Donald L. Jarvis. A new insect cell line engineered to produce recombinant glycoproteins with cleavable N-glycans. Journal of Biological Chemistry. 2021. 101454-101454
-
Motohiro Nonaka, Hideaki Mabashi-Asazuma, Donald L. Jarvis, Kazuhiko Yamasaki, Tomoya O. Akama, Masato Nagaoka, Toshio Sasai, Itsuko Kimura-Takagi, Yoichi Suwa, Takashi Yaegashi, et al. Development of an orally-administrable tumor vasculature-targeting therapeutic using annexin A1-binding D-peptides. PLOS ONE. 2021. 16. 1. e0241157
-
Miori Tanaka, Akari Sato, Yoshimi Kishimoto, Hideaki Mabashi-Asazuma, Kazuo Kondo, Kaoruko Iida. Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes. Nutrients. 2020. 12. 5. 1479-1479
-
松本 萌, 北村 奏乃, ジャネ・エルランガ, 原 奈摘, 坂本 友里, 馬橋 英章, 飯田 薫子. 筋芽細胞C2C12におけるDaidzeinのERRαを介した脂質酸化促進作用の検討. 日本栄養・食糧学会大会講演要旨集. 2020. 74回. 232-232
-
Kanano Kitamura, Jane Surya Erlangga, Sakuka Tsukamoto, Yuri Sakamoto, Hideaki Mabashi-Asazuma, Kaoruko Iida. Daidzein promotes the expression of oxidative phosphorylation- and fatty acid oxidation-related genes via an estrogen-related receptor α pathway to decrease lipid accumulation in muscle cells. The Journal of Nutritional Biochemistry. 2020. 77. 108315-108315
ｍore...
MISC (7)：
-
Hideaki Mabashi-Asazuma, Donald L. Jarvis. Knocking-out fdl gene in a baculovirus host insect cell line using new CRISPR-Cas9 tools for lepidopteran insect cell lines. GLYCOBIOLOGY. 2016. 26. 12. 1452-1452
-
Hideaki Mabashi-Asazuma, Chu-Wei Kuo, Kay-Hooi Khoo, Donald L. Jarvis. Modifying an insect cell N-glycan processing pathway using CRISPR-Cas9 technology. GLYCOBIOLOGY. 2015. 25. 11. 1273-1273
-
Donald Jarvis, Christoph Geisler, Ann Toth, Hideaki Mabashi-Asazuma. Manipulating glycan processing in the baculovirus-insect cell system for diverse biomedical applications. GLYCOBIOLOGY. 2014. 24. 11. 1102-1102
-
Donald Jarvis, Christoph Geisler, Hideaki Mabashi-Asazuma, Ann Toth. Biomedical engineering: An approach that can be effectively used not only to improve, but also to probe insect protein glycosylation pathways. GLYCOBIOLOGY. 2012. 22. 11. 1580-1581
-
Hideaki Mabashi-Asazuma, Christoph Geisler, Donald L. Jarvis. Identifying bottlenecks in efforts to glycoengineer insect cells for humanized Nglycan processing. GLYCOBIOLOGY. 2012. 22. 11. 1596-1596
ｍore...
Professional career (1)：
- 博士(農学) (東京大学大学院農学生命科学研究科)
Work history (5)：
- 2022/04 - 現在 bitBiome, Inc. Research and Development Department Researcher
- 2017/06 - 2022/03 Ochanomizu University
- 2013/10 - 2017/05 GlycoBac, LLC Research Consultant
- 2010/01 - 2017/05 University of Wyoming Department of Molecular Biology Postdoctoral Researcher
- 2008/04 - 2009/12 The University of Tokyo Graduate School of Agricultural and Life Sciences Postdoctoral Researcher
Return to Previous Page
