Rchr
J-GLOBAL ID:201701017156732061
Update date: Dec. 03, 2025
TAKUYA YAMAMOTO
ヤマモト タクヤ | TAKUYA YAMAMOTO
Affiliation and department:
Job title:
Director
Other affiliations (3):
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Osaka University
Graduate School of Medicine
Guest Professor
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Osaka University
Graduate School of Pharmaceutical Sciences
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大阪国際がんセンター
次世代がん医療開発センター がん病態解析室
リサーチディレクター
Homepage URL (1):
https://www.nibn.go.jp/activities/precision-immunology.html
Research theme for competitive and other funds (10):
- 2024 - 2027 COVID-19 mRNAワクチン接種による記憶CD8 T細胞反応誘導メカニズムの解明とその応用
- 2023 - 2026 膵癌における臨床応用を見据えた高次免疫学的解析手法を駆使した免疫微小環境の解析
- 2020 - 2023 HIV感染症の機能的治癒を目指したアジュバント最適型新規免疫療法の確立
- 2020 - 2023 免疫老化を考慮した次世代型インフルエンザワクチン開発の基盤構築
- 2022 - 2023 Establishment and applied research of novel infection model using innovative recombinant SARS-CoV-2 (P2 infection model, In vivo imaging, Mouse infection model)
- 2019 - 2022 The cellular senescence of cancer-associated fibroblast affect the malignant potential in pancreatic cancer
- 2019 - 2021 Development of the non-human primate model for studying the aging of the Immune System
- 2017 - 2020 Study of tuberculosis and development of vaccine in latent infected cynomolgus monkeys.
- 2017 - 2020 Development of new immunotherapy treatments toward a cure for HIV
- 2008 - 2009 HIV感染者において発現が変動するmiRNAの網羅的解析
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Papers (89):
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Shokichi Takahama, Ayaka Washizaki, Tomotaka Okamura, Shingo Kitamura, Takuto Nogimori, Yorifumi Satou, Yasuhiro Yasutomi, Tomokazu Yoshinaga, Takuya Yamamoto. The quality of SIV-specific fCD8 T cells limits SIV RNA production in Tfh cells during antiretroviral therapy. Journal of Virology. 2025
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Gaëlle Autaa, Laura Papagno, Takuto Nogimori, Andrea Boizard-Moracchini, Daniil Korenkov, Maeva Roy, Koichiro Suzuki, Yuji Masuta, Eoghann White, Sian Llewellyn-Lacey, et al. Ageing and inflammation limit the induction of SARS-CoV-2-specific CD8+ T cell responses in severe COVID-19. JCI insight. 2025
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Ayae Nishiyama, Takuto Nogimori, Yuji Masuta, Tomoka Matsuura, Tetsuo Kase, 近藤亨子, Satoko Ohfuji, Yu Nakagama, Natsuko Kaku, Sachie Nakagama, et al. Cross-Reactive Fc-Mediated Antibody Responses to Influenza HA Stem Region in Human Sera Following Seasonal Vaccination. Vaccines. 2025
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Atsushi Kawai, Taro Shimizu, Hiroki Tanaka, Shintaro Shichinohe, Jessica Anindita, Mika Hirose, Eigo Kawahara, Kota Senpuku, Makoto Shimooka, Le Thi Quynh Mai, et al. Low-inflammatory lipid nanoparticle-based mRNA vaccine elicits protective immunity against H5N1 high-pathogenicity avian influenza virus with reduced adverse reactions. Molecular therapy : the journal of the American Society of Gene Therapy. 2024
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Natsuko Kaku, Mayo Yasugi, Evariste Tshibangu-Kabamba, Yoshiyuki Wakabayashi, Yuko Uesaka, Yu Nakagama, Takuto Nogimori, Takuya Yamamoto, Placide Mbala-Kingebeni, Dieudonné Mumba Ngoyi, et al. Multiple-clone infections of Mpox: Insights from a single primary lesion. CMI Communications. 2024. 105042-105042
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Books (1):
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The role of Follicular helper CD4 T cells in HIV/SIV infection
The Japanese Society for Virology 2012
Professional career (1):
- Ph.D (The University of Tokyo)
Work history (4):
- 2023/04 - 現在 National Institutes of Biomedical Innovation, Health and Nutrition Center for Intractable Diseases and ImmunoGenomics Director
- 2021/08 - 現在 Osaka University Graduate School of Medicine
- 2021/05 - 現在 大阪国際がんセンター 次世代がん医療開発センター がん病態解析室 リサーチディレクター
- 2018/11 - 現在 Osaka University Graduate School of Pharmaceutical Sciences
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