Rchr
J-GLOBAL ID：201701018888365840
Update date: Jun. 05, 2025
Kosuke Nakashima
ナカシマ コウスケ | Kosuke Nakashima
Affiliation and department：
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research keywords (3)：
Synthetic Organic Chemistry
, asymmetric reaction
, organocatalyst
Research theme for competitive and other funds (3)：
- 2024 - 2025 Development and application of stimulus-responsive molecules for deep biological imaging
- 2015 - 2017 Research and development of organocatalyst as an artificial acylating enzyme
- 2017 - The development of the Photoswitchable Organic Catalyst
Papers (59)：
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Kosuke Nakashima, Aoi Imamura, Yasuyuki Matsushima, Shin-ichi Hirashima, Dancho Yordanov, Tsuyoshi Miura, Anton Georgiev. Intramolecular through-space conjugation of chiral C2-spirooxindole. Journal of Photochemistry and Photobiology A: Chemistry. 2025
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Eri Sasaki, Yuki Itaya, Yoko Endo-Takahashi, Yusuke Yano, Nobuhito Hamano, Keisuke Hamada, Yamato Kikkawa, Kosuke Nakashima, Rui Tada, Tsuyoshi Miura, et al. Systemic mRNA Delivery into the Muscle of Duchenne Muscular Dystrophy Model Mice Using Alpha-Dystroglycan Binding Peptide Modified Lipid Nanoparticles. Biological and Pharmaceutical Bulletin. 2025. 48. 5. 721-727
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Kosuke Nakashima, Yuichi Okuaki, Misaki Deguchi, Yasuyuki Matsushima, Shin-ichi Hirashima, Tsuyoshi Miura. Asymmetric Synthesis of 3-Spiro-Fused 2-Oxindoles via Organocatalyst/N-Iodosuccinimide/Hydrogen Peroxide-Mediated Oxidative Cyclization. Chemical and Pharmaceutical Bulletin. 2025. 73. 4. 382-387
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Eiki Hirota, Shin-ichi Hirashima, Chika Tadasue, Anna Suzuki, Yasuyuki Matsushima, Kosuke Nakashima, Tsuyoshi Miura. Synthesizing Chiral Vicinal Bisphosphine Derivatives through Hydrophosphinylation and Asymmetric Protonation of Secondary Phosphine Sulfides with Vinylphosphine Oxides. The Journal of Organic Chemistry. 2025
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Ryo Tsuyusaki, Kosuke Nakashima, Yasuyuki Matsushima, Shin-ichi Hirashima, Tsuyoshi Miura. Synthesis of Pyrazolidin-3-one Derivatives Bearing Trifluoromethyl Group via Cascade Michael/Intramolecular Transamidation Reactions. Asian Journal of Organic Chemistry. 2025
ｍore...
Lectures and oral presentations (29)：
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The synthesis and photoluminescence properties of spiro oxindole
(International Conference on Bioactive, Organic and Inorganic Advanced Materials and Clean Technologies 2025)
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β-スルホニルエノンを用いたイソオキサゾール-5-オンのN-選択的アルケニル化反応
(日本薬学会 第145年会 2025)
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非対称DPPE誘導体の位置選択的ワンポット合成法の開発
(第50回 反応と合成の進歩シンポジウム 2024)
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新規求電子剤を用いたCF3基含有pyrazolidin-3-one誘導体合成法の開発
(第50回 反応と合成の進歩シンポジウム 2024)
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有機分子触媒を用いたCF3 基含有スピロインダン-1,3-ジオン誘導体の不斉合成
(第68回 日本薬学会 関東支部大会 2024)
ｍore...
Education (2)：
- 2010 - 2012 Gifu Pharmaceutical University Graduate School Department of Pharmaceutical Science Master's Program
- 2006 - 2010 Gifu Pharmaceutical University Faculty of Pharmaceutical Science Faculty of Pharmaceutial Science
Professional career (1)：
Work history (5)：
- 2022/04 - 現在 東京薬科大学 薬学部 医療薬物薬学科 薬化学教室 講師
- 2017/04 - 2022/03 Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy Assistant Professor
- 2018/05 - 2019/11 Humboldt-Universität zu Berlin Department of Chemistry & IRIS Adlershof Postdoctoral researcher
- 2013/07 - 2017/03 Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy assistant researcher
- 2012/04 - 2013/06 KATAYAMA SEIYAKUSHO Research and deveplopment division researcher
Association Membership(s) (1)：
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