Hashimoto Misuzu

ハシモトミスズ | Hashimoto Misuzu

Affiliation and department：
Other affiliations (1)：

Gifu University The United Graduate School of Agricultural Science assistant professor

Homepage URL (1)： http://www.abios.gifu-u.ac.jp/nakagawa/

Research field (1)： Molecular biology

Research keywords (12)： Atp6ap2 , PRMT1 , neural stem cell , cerebellum , prorenin receptor , myelin , post translational modification , central nervous system , neural development , pregnancy associated hypertension , glia , arginine methylation

Research theme for competitive and other funds (8)：

2023 - 2026 The role of protein arginine methyl transferase PRMT1 on myelin development
2023 - 2025 タンパク質アルギニンメチル化による中枢神経ミエリンの発生・再生制御機構の解明
2022 - 2023 Identification of arginine methylated proteins responsible for the central nervous system mylination
2020 - 2023 Mechanistic analyses how arginine methylation drives cerebellar development
2020 - 2022 メチル化修飾分子の同定による中枢神経ミエリン形成メカニズムの解明

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Papers (12)：

Misuzu Hashimoto, Kaho Takeichi, Kazuya Murata, Aoi Kozakai, Atsushi Yagi, Kohei Ishikawa, Chiharu Suzuki-Nakagawa, Yoshitoshi Kasuya, Akiyoshi Fukamizu, Tsutomu Nakagawa. Regulation of neural stem cell proliferation and survival by protein arginine methyltransferase 1. Frontiers in Neuroscience. 2022. 16
Nariyasu Tahara, Itaru Tachibana, Kazuyo Takeo, Shinji Yamashita, Atsuhiro Shimada, Misuzu Hashimoto, Satoshi Ohno, Takashi Yokogawa, Tsutomu Nakagawa, Fumiaki Suzuki, et al. Boosting Auto-induction of Recombinant Proteins in Escherichia coli with Glucose and Lactose Additives. Protein and peptide letters. 2021. 28. 10. 1180-1190
Misuzu Hashimoto, Akiyoshi Fukamizu, Tsutomu Nakagawa, Yasuhiko Kizuka. Roles of protein arginine methyltransferase 1 (PRMT1) in brain development and disease. Biochimica et biophysica acta. General subjects. 2020. 1865. 1. 129776-129776
Misuzu Hashimoto, Ayako Kumabe, Jun-Dal Kim, Kazuya Murata, Sowmya Sekizar, Anna Williams, Weizhe Lu, Junji Ishida, Tsutomu Nakagawa, Mitsuharu Endo, et al. Loss of PRMT1 in the CNS induces reactive astrocytes and microglia during postnatal brain development. Journal of Neurochemistry. 2020
Misuzu Hashimoto, Tetsuya Hirata, Chizuko Yonekawa, Kaho Takeichi, Akiyoshi Fukamizu, Tsutomu Nakagawa, Yasuhiko Kizuka. Region-specific upregulation of HNK-1 glycan in the PRMT1-deficient brain. Biochimica et Biophysica Acta (BBA) - General Subjects. 2020. 1864. 3. 129509-129509

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MISC (12)：

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Lectures and oral presentations (11)：

Decoding protein arginine methylation in brain development
(2023)
PRMT1 regulates alternative splicing of Atg16l1 gene in the central nervous system
(The 95th Annual Meeting of the Japanese Biochemical Society 2022)
PRMT1欠損は生後の脳においてアストロサイトやミクログリアの活性化を引き起こす
(第85回日本生化学会中部支部例会・シンポジウム 2021)
神経幹細胞特異的PRMT1欠損マウスにおけるグルタミン酸-グルタミンサイクル
(第91回日本生化学会大会 2018)
A role of protein arginine methyltransferase 1 (PRMT1) in the generation of CNS glia
(The 41st annual meeting of the Japan Neuroscience Society 2018)

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Education (2)：

2012 - 2017 University of Tsukuba Ph.D. Program in Human Biology
2008 - 2012 University of Tsukuba

Professional career (1)：

Ph.D. in Human Biology (University of Tsukuba)

Work history (2)：

2017/04 - 現在 Gifu University Faculty of Applied Biological Sciences Assistant professor
2023/04 - 2025/03 岐阜大学グローカル推進機構部門員

Committee career (1)：

2021/04 - 現在 Frontiers in Neuropharmacology Review Editor

Association Membership(s) (5)：

JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE , 日本心血管内分泌代謝学会 , THE JAPANESE BIOCHEMICAL SOCIETY , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , THE JAPAN NEUROSCIENCE SOCIETY

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