Sakurai Toshihiro

Affiliation and department：

Research field (5)： Food sciences , Metabolism and endocrinology , Nutrition and health science , Gastroenterology , Other

Research keywords (10)： LDL-TG , HDL , LDL , 肝臓 , 分析 , 臨床検査 , 食品 , 酸化ストレス , Lipoprotein , Lipid

Research theme for competitive and other funds (8)：

2023 - 2026 Development and application of novel technique for evaluation of mitochondrial function
2022 - 2025 ミトコンドリア機能障害に着目した酸化HDLとNASH発症機序の関連解明
2023 - 2024 -
2019 - 2022 酸化HDLに焦点を当てたNASHの発症機序の解明と診断マーカーの探索
2019 - 2020 ミトコンドリア代謝の包括的評価系の開発

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Papers (57)：

Akiko Sakurai, Toshihiro Sakurai, Hsin-Jung Ho, Hitoshi Chiba, Shu-Ping Hui. Kaempferol Improves Cardiolipin and ATP in Hepatic Cells: A Cellular Model Perspective in the Context of Metabolic Dysfunction-Associated Steatotic Liver Disease. Nutrients. 2024. 16. 4
Dya Fita Dibwe, Nire Takeishi, Saki Oba, Akiko Sakurai, Toshihiro Sakurai, Takayuki Tsukui, Hitoshi Chiba, Shu-Ping Hui. Identification of a β-Carboline Alkaloid from Chemoselectively Derived Vanilla Bean Extract and Its Prevention of Lipid Droplet Accumulation in Human Hepatocytes (HepG2). Molecules. 2023. 28. 24. 8024-8024
Hsin-Jung Ho, Natsumi Aoki, Yi-Jou Wu, Ming-Chen Gao, Karin Sekine, Toshihiro Sakurai, Hitoshi Chiba, Hideaki Watanabe, Mitsugu Watanabe, Shu-Ping Hui. A Pacific Oyster-Derived Antioxidant, DHMBA, Protects Renal Tubular HK-2 Cells against Oxidative Stress via Reduction of Mitochondrial ROS Production and Fragmentation. International journal of molecular sciences. 2023. 24. 12
Iku Sazaki, Toshihiro Sakurai, Arisa Yamahata, Sumire Mogi, Nao Inoue, Koutaro Ishida, Ami Kikkai, Hana Takeshita, Akiko Sakurai, Yuji Takahashi, et al. Oxidized Low-Density Lipoproteins Trigger Hepatocellular Oxidative Stress with the Formation of Cholesteryl Ester Hydroperoxide-Enriched Lipid Droplets. International Journal of Molecular Sciences. 2023. 24. 5. 4281-4281
櫻井俊宏, 惠淑萍. リゾホスファチジルエタノールアミンと肝疾患. 臨床化学51巻3号. 2022

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MISC (171)：

Sakurai A, Sakurai T, Ho HJ, Chiba H, Hui SP. Enhancement of mitochondrial function with kaempferol, contained as glycoside in Aojiru. The Indian Scientists Association in Japan. 2023
Inoue N, Gowda SGB, Gowda D, Sakurai T, Ketema RM, Ikeda A, Chiba H, Hui SP. Determination of plasma lysophosphatidylethanolamine levels in preadolescent children. The 6th FHS International Conference. 2023
Search for, Oxidized High-Density Lipoprotein Receptor in, Human Liver-Derived Cell Line. Sasa M, Sakurai T, Ishida K, Chiba H, Hui SP. The 6th FHS International Conference. 2023
Masuko N, Sakurai T, Yamahata A, Sazaki I, Mogi S, Chiba H, Hui SP. Lipidomic Analysis of Very-Low Density Lipoprotein Released from Human Liver-Derived Cell Line. The 6th FHS International Conference. 2023
Takeshita H, Sakurai T, Gowda SGB, Chiba H, Hui SP. The effect of 12-EPAHSA on mitochondrial morphology in fatty liver model cells. The 6th FHS International Conference. 2023

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Books (2)：

知っておきたい臨床検査値第2版
東京化学同人 2019
Medical Technology
医歯薬出版 2010

Lectures and oral presentations (10)：

道産食材の機能性の探索
(健康食品管理士会北海道支部秋季研修会/市民公開講座 2023)
尿中コレステリルエステルと腎障害の関連
(第7回日本医用マススペクトル学会東部会 2022)
NASH鑑別マーカーとしての血中LDL-TG値の有用性
(第60回日本臨床化学会年次学術集会, YIAシンポジウム 2020)
LDL-TG測定試薬の臨床検体への応用
(第58回日本臨床化学会年次学術集会若手育成シンポジウム 2018)
研究留学を振り返って
(北海道大学大学院保健科学研究院保健科学セミナー 2016)

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Education (4)：

2010 - 2013 Hokkaido University Graduate School of Health Sciences
2008 - 2010 Hokkaido University Graduate School of Health Sciences
2006 - 2008 Hokkaido University School of Medicine Department of Health Sciences
2003 - 2006 Hokkaido University

Professional career (1)：

博士(保健科学) (北海道大学)

Work history (6)：

2022/04 - 現在 Faculty of Health Sciences, Hokkaido University
2016/11 - 2022/03 Hokkaido University Faculty of Health Sciences
2016/06 - 2016/10 Hokkaido University Faculty of Health Sciences
2013/06 - 2016/05 National Institutes of Health
2013/04 - 2013/05 北海道大学保健科学研究院惠淑萍研究室博士研究員

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Committee career (6)：

2023/04 - 現在健康食品管理士会北海道支部, 副支部長
2019/09 - 現在日本臨床化学会 [JSCC] リポ蛋白検査専門委員会
2019/04 - 現在健康食品管理士会北海道支部幹事役員
2019/04 - 現在日本医用マススペクトル学会 [JSBMS] 評議員
2017/04 - 現在日本臨床化学会 [JSCC] 評議員

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Awards (9)：

2020/10 - 日本臨床化学会日本臨床化学会学会賞 Young Investigator Award
2019/10 - 第29回日本臨床化学会北海道支部例会若手優秀演題賞
2018/09 - 第43回日本医用マススペクトル学会年会若手優秀ポスター賞
2018/05 - 北海道大学大学院保健科学研究院優秀論文賞
2016/05 - ATVB Young Investigator Travel Award 2016

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Association Membership(s) (5)：

日本食品安全協会 , JAPANESE SOCIETY FOR BIOMEDICAL MASS SPECTROMETRY , JAPANESE SOCIETY OF LABORATORY MEDICINE , JAPAN SOCIETY OF CLINICAL CHEMISTRY , American Association for Clinical Chemistry

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