Kanki Tomotake

カンキトモタケ | Kanki Tomotake

Affiliation and department：
Job title：教授
Homepage URL (1)： https://www.med.niigata-u.ac.jp/mit/

Research field (3)： Pathobiochemistry , Medical biochemistry , Cell biology

Research keywords (3)： mitophagy , autophagy , mitochondria

Research theme for competitive and other funds (21)：

2022 - 2025 レセプター依存的マイトファジーの誘導制御と生理機能の解明
2019 - 2024 多様なマイトファジーの分子機構と生理的意義の解明
2019 - 2022 Proteins escape from autophagic degradation
2018 - 2020 マイトファジーレセプターAtg32のリン酸化制御機構の解明
2018 - 2020 ミトコンドリア分解ゾーンの形成機構と分解基質の解明

Show all

Papers (79)：

Shun-Ichi Yamashita, Yuki Sugiura, Yuta Matsuoka, Rae Maeda, Keiichi Inoue, Kentaro Furukawa, Tomoyuki Fukuda, David C Chan, Tomotake Kanki. Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species. Cell death and differentiation. 2024
Kyota Aoyagi, Chiyono Nishiwaki, Yoko Nakamichi, Shun-ichi Yamashita, Tomotake Kanki, Mica Ohara-Imaizumi. Imeglimin mitigates the accumulation of dysfunctional mitochondria to restore insulin secretion and suppress apoptosis of pancreatic β-cells from db/db mice. Scientific Reports. 2024. 14. 1
Yen Teng Tai, Tomoyuki Fukuda, Yuichi Morozumi, Hayato Hirai, Arisa H Oda, Yoshiaki Kamada, Yutaka Akikusa, Tomotake Kanki, Kunihiro Ohta, Kazuhiro Shiozaki. Fission Yeast TORC1 Promotes Cell Proliferation through Sfp1, a Transcription Factor Involved in Ribosome Biogenesis. Molecular and cellular biology. 2023. 1-18
Tomoyuki Fukuda, Kentaro Furukawa, Tatsuro Maruyama, Nobuo N Noda, Tomotake Kanki. Mitofissin: a novel mitochondrial fission protein that facilitates mitophagy. Autophagy. 2023. 19. 11. 3019-3021
Tatsuya Shioda, Ittetsu Takahashi, Kensuke Ikenaka, Naonobu Fujita, Tomotake Kanki, Toshihiko Oka, Hideki Mochizuki, Adam Antebi, Tamotsu Yoshimori, Shuhei Nakamura. Neuronal MML-1/MXL-2 regulates systemic aging via glutamate transporter and cell nonautonomous autophagic and peroxidase activity. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 39. e2221553120

ｍore...

MISC (16)：

塩田達也, 池中健介, 神吉智丈, 岡敏彦, 望月秀樹, ANTEBI Adam, 吉森保, 吉森保, 吉森保, 中村修平, et al. 転写因子MML-1/MXL-2による組織間コミュニケーションを介した寿命制御機構の解明. 基礎老化研究. 2023. 47. 2
古川健太郎, 神吉智丈. リン酸化が制御する出芽酵母のマイトファジー. 生化学. 2019. 91. 2. 224-227
山下俊一, 神吉智丈. 【オートファジーと疾患】ミトコンドリア恒常性の維持とマイトファジー. BIO Clinica. 2018. 33. 7. 617-621
CHERNYSHOVA Kseniia, CHERNYSHOVA Kseniia, 山下俊一, 五十嵐遼子, 五十嵐遼子, 福地健郎, 神吉智丈. 広義原発開放隅角緑内障の原因遺伝子オプチニューリン遺伝子の変異とミトコンドリア恒常性維持機構との関係. 日本緑内障学会抄録集. 2018. 29th
神吉智丈. 【オートファジーと疾患】 Parkinに依存しないマイトファジー. 最新医学. 2017. 72. 2. 205-210

ｍore...

Books (2)：

Handbook of Famine, Starvation, and Nutrient Deprivation || Chapter 64-1
2017
AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, and Infection Volume 4: Mitophagy
2014

Education (2)：

2000 - 2003 九州大学大学院医学研究科(博士(医学))
1991 - 1997 Kyushu University School of Medicine

Professional career (1)：

博士(医学) (九州大学)

Work history (9)：

2015/04 - 現在 Niigata University Graduate School of Medical and Dental Sciences
2012/07 - 2015/03 Niigata University Graduate School of Medical and Dental Sciences
2009/04 - 2012/06 九州大学病院検査部・助教
2007/04 - 2009/03 ミシガン大学博士研究員
2005/10 - 2007/03 Columbia University

Show all

Awards (1)：

2012/04 - 文部科学省文部科学大臣表彰若手科学者賞

Association Membership(s) (6)：

酵母遺伝学フォーラム , THE JAPANESE SOCIETY OF MITOCHONDRIAL RESEARCH AND MEDICINE , JAPAN SOCIETY OF OBSTETRICS AND GYNECOLOGY , THE JAPANESE BIOCHEMICAL SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , JAPAN SOCIETY FOR CELL BIOLOGY

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page