Rchr
J-GLOBAL ID：201701020054880520
Update date: Jul. 03, 2025
Masanori Nagatomo
ナガトモ マサノリ | Masanori Nagatomo
Affiliation and department：
Job title：
Professor
Homepage URL (2)：
https://www.pharm.hokudai.ac.jp/tengo_105/
,
https://www.pharm.hokudai.ac.jp/tengo_105/home-en/
Research field (4)：
Bioorganic chemistry
, Structural/physical organic chemistry
, Synthetic organic chemistry
, Pharmaceuticals - chemistry and drug development
Research keywords (5)：
Organic Synthetic Chemistry
, Natural Product Synthesis
, Taotal Synthesis
, Photochemistry
, Computational Chemistry
Research theme for competitive and other funds (14)：
- 2025 - 2028 天然物主導型電位依存性ナトリウムチャネル制御因子の創製
- 2022 - 2025 Unified total synthesis of the unexplored densely oxygenated daphnane diterpenes for drug lead discovery
- 2022 - 2024 Development of Innovative Photoreactions with MI Implementation: Presentation and Realization of an Unexplored Retrosynthetic Strategy for Highly Oxidized Natural Products
- 2022 - 2023 Toward the Total Synthesis of Trigocherrins
- 2017 - 2022 Application of hybrid catalysis-mediated multi-component coupling reactions for efficient construction of densely functionalized natural products
- 2017 - 2022 Expanding the medicinally relevant chemical space with architecturally complex natural products and their synthetic analogues
- 2019 - 2021 Development of strategy toward the unified total synthesis of natural and artificial daphnan/tigrian diterpenoids and discovery of new functional molecules
- 2018 - 2020 Total synthesis and advanced reaction integration of the densely functionalized medium molecular terpenoids by synthetic strategies based on radical reactions
- 2016 - 2019 Development of convergent synthetic strategies of nucleic acid-based natural products utilizing the key three types of radical intermolecular C-C bond formation
- 2017 - 2018 イオンチャネルを制御する巨大複雑天然物の網羅的全合成および新機能分子の創出
- 2015 - 2017 Unified total synthesis and biological evaluation of natural and artificial ryanoids
- 2014 - 2017 Development and Application of Convergent Strategies for Unified Total Syntheses of Architecturally Complex Natural Products
- 2014 - 2016 Establishment of novel synthetic strategy utilizing two types of photo-induced direct C(sp3)-H functionalization
- 2010 - 2012 a study towards total synthesis of ryanodine
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Papers (52)：
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Masanori Nagatomo. My circumstances shape me, and I cultivate my environment. Journal of Synthetic Organic Chemistry, Japan. 2025. 83. 7. 666-669
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Yutaro Yamada, Risa Yoshinaga, Yuki Matsui, Masanori Nagatomo, Haruka Fujino, Masayuki Inoue. Et3Al/Light-Promoted Radical-Polar Crossover Reactions of α-Alkoxyacyl Tellurides. The Journal of Organic Chemistry. 2024
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Ayumu Watanabe, Yuto Hikone, Masanori Nagatomo, Masayuki Inoue. Conversion of Phorbol into Des-D-Ring Tricycle and Crotonianoid B via Peroxidation Reaction. Organic Letters. 2024. 26. 20. 4335-4339
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Ayumu Watanabe, Masanori Nagatomo, Akira Hirose, Yuto Hikone, Naoki Kishimoto, Satoshi Miura, Tae Yasutake, Towa Abe, Shogo Misumi, Masayuki Inoue. Total Syntheses of Phorbol and 11 Tigliane Diterpenoids and Their Evaluation as HIV Latency-Reversing Agents. Journal of the American Chemical Society. 2024. 146. 12. 8746-8756
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Yuto Hikone, Masanori Nagatomo, Masayuki Inoue. Development of Streamlined Processes for Construction of Complex Natural Products: Three Total Syntheses of Resiniferatoxin. Journal of Synthetic Organic Chemistry, Japan. 2023. 81. 12. 1136-1149
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MISC (81)：
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松本真那果, 高岡恭兵, 長友優典, 萩原浩一, 井上将行. Synthetic study of maprouneacin. 日本薬学会年会要旨集(Web). 2024. 144th
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高岡恭兵, 長友優典, 萩原浩一, 井上将行. Synthetic study of trigocherrin A. 日本薬学会年会要旨集(Web). 2024. 144th
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長友優典. Unified Total Synthesis of Daphnane, Tigliane, and Rhamnopholane Diterpenoids. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
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長友優典. Unified Total Synthesis of Daphnane, Tigliane, and Rhamnopholane Diterpenoids. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
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HAN Jaejoong, 長友優典, 井上将行. Synthetic study of daphnetoxin. 日本薬学会年会要旨集(Web). 2023. 143rd
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Books (13)：
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Exploration of the Unified Total Synthetic Strategies-Unraveling and Assembling Privileged Structures
The Chemical Society of Japan 2023
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Total Syntheses of Densely Oxygenated Natural Products by Radical-Based Decarbonylative Convergent Assembly
Springer 2023 ISBN:9789819917136
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抗がん剤タキソールの全合成--ラジカル反応を活用した新しい合成戦略とその展開
化学同人 2023
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α-Arylation of Cyclopentanones by Palladium/Enamine Cooperative Catalysis
Organic Syntheses, Inc. 2023
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Stereoselective [2+2] Cycloadditions: Synthesis ofa Tri-O-Bn-D-Glucal-derived β-Lactam
Organic Syntheses, Inc. 2021
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Education (4)：
- 2009 - 2012 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Integrated Pharmaceutical Sciences
- 2007 - 2009 Tokyo University of Science Graduate School of Science Department of Chemistry
- 2003 - 2007 Tokyo University of Science Faculty of Science, Division 1 Department of Applied Chemistry
- 1999 - 2002 Miyazaki Prefectural Miyazaki Nishi High School Science and Mathematics Course
Professional career (1)：
- Ph.D. (The University of Tokyo)
Work history (6)：
Committee career (2)：
- 2018/04 - 現在 Colloquium of natural product chemistry manager
- 2018/04 - 現在 天然物化学談話会 世話人
Awards (10)：
- 2025/04 - UBE Foundation for the Promotion of Science UBE Foundation for the Promotion of Science Academic Encouragement Award 2025
- 2024/04 - Nagase Science and Technology Foundation Nagase Foundation Award 2024
- 2023/03 - The Chemical Society of Japan 37th Young Scholar Lecture Award Unified Total Synthesis of Daphnane, Tigliane, and Rhamnopholane Diterpenoids
- 2021/12 - The Society of Synthetic Organic Chemistry, Japan Daiichi Sankyo Research Proposal Award
- 2021/10 - The University of Tokyo The University of Tokyo Excellent Young Researcher Simplification of the Synthesis of Densely Oxygenated Bioactive Natural Products Based on Radical Synthetic Strategies
- 2019/12 - MSD Life Science Foundation, Public Interest Incorporated Foundation Chemist Award BCA 2019 Development of novel C-C bond formation reactions utilizing α-alkoxy and α-amino carbon radical and application to the total synthesis of densely oxygenated natural products
- 2019/01 - Thieme Publishing Group The Thieme Chemistry Journals Award 2019
- 2018/03 - The pharmaceutical society of Japan The Pharmaceutical Society of Japan Award for Young Scientists '18 Development of synthetic strategies for densely oxygenated natural product
- 2017/07 - Colloquium of natural product chemistry Young Scientist’s Research Award in Natural Product Chemistry Development of synthetic strategies for densely functionalized natural product
- 2010/12 - Pacifichem 2010 Student Poster Competition Award Synthetic Study of Ryanodine
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Association Membership(s) (5)：
THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN
, THE CHEMICAL SOCIETY OF JAPAN
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, Japan Society for Bioscience, Biotechnology, and Agrochemistry
, The Japanese Society of Pharmacognosy
