Rchr
J-GLOBAL ID:201701020746591146
Update date: Sep. 21, 2024
Shiromizu Takashi
シロミズ タカシ | Shiromizu Takashi
Affiliation and department:
Job title:
助教
Homepage URL (1):
https://mie-integrative-pharm.tumblr.com/
Research field (4):
Tumor biology
, Laboratory animal science
, Molecular biology
, Pharmacology
Research keywords (4):
Cancer
, Primary Cillia
, Zebrafish
, Proteomics
Research theme for competitive and other funds (9):
- 2023 - 2026 Elucidation of the mechanism of muscle regeneration regulated by primary cilia of mesenchymal progenitors
- 2022 - 2025 ゼブラフィッシュのプロテオーム解析による一次線毛動態制御因子の探索と機能解析
- 2020 - 2023 Regulation of primary cilia formation by the ubiquitin–proteasome system
- 2019 - 2022 複合的アプローチを用いた多発性嚢胞腎の新規病態メカニズム解明
- 2018 - 2021 一次線毛の動態制御によるがん治療法開発を志向したマルチオミックス解析
- 2015 - 2018 Elucidation of gene expression regulation mechanism in cancer cells focusing on multifunctionality of Importin-alpha
- 2015 - 2018 Biomarker discovery of colorectal cancer metastasis from cancer tissues and verification in plasma exosomes by targeted proteomics.
- 2013 - 2015 Establishment of highly metastatic colorectal cancer cells and phosphoproteomic analysis for biomarker discovery.
- 2011 - 2013 Phosphoproteomic analysis of clinical colon cancer specimen and validation by SRM/MRM analysis.
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Papers (30):
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Eri Wakai, Takashi Shiromizu, Shota Otaki, Junko Koiwa, Satoshi Tamaru, Yuhei Nishimura. Lansoprazole Ameliorates Isoniazid-Induced Liver Injury. Pharmaceuticals (Basel, Switzerland). 2024. 17. 1
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Yuka Adachi, Aina Higuchi, Eri Wakai, Takashi Shiromizu, Junko Koiwa, Yuhei Nishimura. Involvement of homeobox transcription factor Mohawk in palatogenesis. Congenital anomalies. 2022. 62. 1. 27-37
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Yuhei Nishimura, Daishi Yamakawa, Takashi Shiromizu, Masaki Inagaki. Aurora A and AKT Kinase Signaling Associated with Primary Cilia. Cells. 2021. 10. 12
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Aina Higuchi, Eri Wakai, Tomoko Tada, Junko Koiwa, Yuka Adachi, Takashi Shiromizu, Hidemasa Goto, Toshio Tanaka, Yuhei Nishimura. Generation of a Transgenic Zebrafish Line for In Vivo Assessment of Hepatic Apoptosis. Pharmaceuticals (Basel, Switzerland). 2021. 14. 11
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Yuhei Nishimura, Daishi Yamakawa, Katsunori Uchida, Takashi Shiromizu, Masatoshi Watanabe, Masaki Inagaki. Primary cilia and lipid raft dynamics. Open biology. 2021. 11. 8. 210130-210130
more...
MISC (25):
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冨山 栄輔, 藤田 和利, 松崎 恭介, 白水 崇, 鳴海 良平, 神宮司 健太郎, 加藤 大悟, 波多野 浩士, 河嶋 厚成, 氏家 剛, et al. 尿中および組織分泌細胞外小胞のプロテオミクス解析による新規膀胱癌バイオマーカーの探索. 日本分子腫瘍マーカー研究会誌. 2022. 37. 16-17
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冨山 栄輔, 藤田 和利, 松崎 恭介, 白水 崇, 鳴海 良平, 神宮司 健太郎, 加藤 大悟, 波多野 浩士, 河嶋 厚成, 氏家 剛, et al. 尿中および組織分泌細胞外小胞のプロテオミクス解析による新規膀胱癌バイオマーカーの探索. 日本分子腫瘍マーカー研究会プログラム・講演抄録. 2021. 41回. 50-51
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HIGUCHI Aina, WAKAI Eri, ADACHI Yuka, TADA Tomoko, KOIWA Junko, SHIROMIZU Takashi, TANAKA Toshio, NISHIMURA Yuhei. Generation of a transgenic zebrafish line suitable for in vivo imaging of apoptosis in liver. 日本薬理学会年会要旨集(Web). 2021. 94th
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ADACHI Yuka, KOIWA Junko, SHIROMIZU Takashi, TANAKA Toshio, NISHIMURA Yuhei. Assessment of Developmental Neurotoxicity during Neuronal Differentiation using a Triple-Transgenic Zebrafish Line. 日本薬理学会年会要旨集(Web). 2020. 93rd
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白水 崇, 三浦 亘揮, 西村 有平. オミクスデータを用いた多発性嚢胞腎の新規病態メカニズム解析. 血管. 2019. 42. 1. 50-50
more...
Patents (2):
Books (2):
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プロテオミクス辞典
講談社 2013 ISBN:9784061538931
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タンパク質の翻訳後修飾解析プロトコール : リン酸化, 糖鎖修飾, ユビキチン化, アセチル化, メチル化, 脂質修飾の解析方法を網羅!
羊土社 2006 ISBN:489706418X
Education (3):
- 2002 - 2006 Nagoya University Graduate School of Medicine
- 2000 - 2002 Nara Institute of Science and Technology
- 1996 - 2000 Hokkaido University School of Science Biological Sciences
Professional career (1):
Work history (3):
- 2017/07 - 現在 Mie University Graduate School of Medicine Department of Integrative Pharmacology Assistant Professor
- 2010/04 - 2017/06 National Institutes of Biomedical Innovation, Health and Nutrition Laboratory of Proteome Research Postdoctoral associate
- 2006/04 - 2010/03 Aichi Cancer Center, Research Institute Division of Biochemistry Research Resident
Association Membership(s) (4):
日本プロテオーム学会
, 日本癌学会
, 日本薬理学会
, 日本心脈管作動物質学会
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