Hiroshima Yukihiko

ヒロシマユキヒコ | Hiroshima Yukihiko

Affiliation and department：
Other affiliations (1)：

横浜市立大学医学部医学科がん総合医科学客員講師

Research field (1)： Tumor biology

Research keywords (6)：神経内分泌腫瘍 , 転移 , 浸潤 , Patient derived xenograft , 微小環境 , 膵癌

Research theme for competitive and other funds (8)：

2019 - 2022 膵癌における癌局所免疫が果たす役割の解明
2019 - 2022 膵癌微小環境におけるTGFβシグナリングの制御と腫瘍免疫との関連
2017 - 2020 膵癌・膵前癌病変における神経軸索ガイダンス因子CRMP4の機能の解明
2016 - 2019 ALPPS手術による残肝容量増大メカニズムの解明
2014 - 2017 膵癌間質のプロテオーム解析継続

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Papers (93)：

Kei Sato, Ryutaro Mori, Yukihiko Hiroshima, Mari S. Oba, Ryusei Matsuyama, Michael Bouvet, Robert M. Hoffman, Itaru Endo. RT-PCR of peritoneal washings predicts peritoneal pancreatic cancer recurrence. Journal of Surgical Research. 2018. 226. I-V
Kentaro Miyake, Kei Kawaguchi, Masuyo Miyake, Ming Zhao, Tasuku Kiyuna, Kentaro Igarashi, Zhiying Zhang, Takashi Murakami, Yunfeng Li, Scott D. Nelson, et al. Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations. Heliyon. 2018. 4. 6. e00643
Kentaro Miyake, Kei Kawaguchi, Tasuku Kiyuna, Masuyo Miyake, Kentaro Igarashi, Zhiying Zhang, Takashi Murakami, Yunfeng Li, Scott D. Nelson, Irmina Elliott, et al. Regorafenib regresses an imatinib-resistant recurrent gastrointestinal stromal tumor (GIST) with a mutation in exons 11 and 17 of c-kit in a patient-derived orthotopic xenograft (PDOX) nude mouse model. Cell Cycle. 2018. 17. 6. 722-727
Takashi Murakami, Yukihiko Hiroshima, Yong Zhang, Ming Zhao, Tasuku Kiyuna, Ho Kyoung Hwang, Kentaro Miyake, Yuki Homma, Ryutaro Mori, Ryusei Matsuyama, et al. Tumor-Targeting Salmonella typhimurium A1-R Promotes Tumoricidal CD8(+) T Cell Tumor Infiltration and Arrests Growth and Metastasis in a Syngeneic Pancreatic-Cancer Orthotopic Mouse Model. JOURNAL OF CELLULAR BIOCHEMISTRY. 2018. 119. 1. 634-639
Kentaro Miyake, Takashi Murakami, Tasuku Kiyuna, Kentaro Igarashi, Kei Kawaguchi, Yunfeng Li, Arun S. Singh, Sarah M. Dry, Mark A. Eckardt, Yukihiko Hiroshima, et al. Eribulin regresses a doxorubicin-resistant Ewing's sarcoma with a FUS-ERG fusion and CDKN2A-deletion in a patient-derived orthotopic xenograft (PDOX) nude mouse model. JOURNAL OF CELLULAR BIOCHEMISTRY. 2018. 119. 1. 967-972

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Education (1)：

2009 - 2013 Yokohama City University

Professional career (1)：

博士(医学) (横浜市立大学)

Work history (3)：

2019/04 - 現在 Kanagawa Cancer Center, Research Institute
2017/04 - 2019/03 Yokohama City University Hospital, Clinical Oncology
2011/11 - 2014/10 University of California, San Diego

Association Membership(s) (7)：

ASCO , AACR , THE JAPANESE SOCIETY OF GASTROENTEROLOGICAL SURGERY , JAPAN SURGICAL SOCIETY , 日本臨床腫瘍学会 , JAPAN SOCIETY OF CLINICAL ONCOLOGY , THE JAPANESE CANCER ASSOCIATION

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