Nishigaya Yuki

ニシガヤユウキ | Nishigaya Yuki

Affiliation and department：

Research field (1)： Structural biochemistry

Research keywords (5)： Solution NMR , X-ray crystal analysis , Structure biology , Structure based design , Developing pesticide

Research theme for competitive and other funds (12)：

2021 - 2026 持続的農業に貢献する分子標的型硝化抑制剤の開発
2022 - 2024 構造ベース創農薬による新規硝化抑制剤の開発
2022 - 2023 安全な分子標的農薬を実現する創農薬プラットフォームの確立
2020 - 2021 -
2020 - 2021 医薬開発技術の導入による安全性の高い除草剤の創出

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Papers (5)：

Yukie Akutsu, Takaaki Fujiwara, Rintaro Suzuki, Yuki Nishigaya, Toshimasa Yamazaki. Juglone, a plant-derived 1,4-naphthoquinone, binds to hydroxylamine oxidoreductase and inhibits the electron transfer to cytochrome c554. Applied and environmental microbiology. 2023. e0129123
Yoshikazu Shimoda, Yuki Nishigaya, Hiroko Yamaya-Ito, Noritoshi Inagaki, Yosuke Umehara, Hideki Hirakawa, Shusei Sato, Toshimasa Yamazaki, Makoto Hayashi. The rhizobial autotransporter determines the symbiotic nitrogen fixation activity of Lotus japonicus in a host-specific manner. Proceedings of the National Academy of Sciences of the United States of America. 2020. 117. 3. 1806-1815
Beata Gąsowska-Bajger, Yuki Nishigaya, Krystyna Hirsz-Wiktorzak, Anna Rybczyńska, Toshimasa Yamazaki, Hubert Wojtasek. Interference of carbidopa and other catechols with reactions catalyzed by peroxidases. Biochimica et biophysica acta. General subjects. 2018. 1862. 7. 1626-1634
Haruna Takao, Kei Hirabayashi, Yuki Nishigaya, Haruna Kouriki, Tetsuko Nakaniwa, Yoshinori Hagiwara, Jiro Harada, Hideaki Sato, Toshimasa Yamazaki, Yoichi Sakakibara, et al. A substrate-bound structure of cyanobacterial biliverdin reductase identifies stacked substrates as critical for activity. Nature communications. 2017. 8. 14397-14397
Yuki Nishigaya, Zui Fujimoto, Toshimasa Yamazaki. Optimized inhibition assays reveal different inhibitory responses of hydroxylamine oxidoreductases from beta- and gamma-proteobacterial ammonium-oxidizing bacteria. Biochemical and biophysical research communications. 2016. 476. 3. 127-33

MISC (1)：

T Kobayashi, Y Nishigaya, M Mishima, R Tabata, K Akagi, N Sakai, E Katoh, M Takano, T Yamazaki, C Kojima. Structural studies of phytochrome B using solution NMR spectroscopy. PLANT AND CELL PHYSIOLOGY. 2006. 47. S122-S122

Patents (1)：

酸化還元酵素の活性測定方法

Education (4)：

2011 - 2016 東京大学大学院新領域創成科学研究科先端生命科学専攻(連携大学院:農研機構)
2006 - 2011 Nara Institute of Science and Technology Graduate School of Biological Sciences
2004 - 2006 NAIST Bioscience
2000 - 2004 Shizuoka University

Professional career (1)：

Ph.D.

Work history (4)：

2018/03 - 現在 AgroDesign Studio Inc. Founder&CEO
2017/04 - 2020/03 National Agriculture and Food Research Organization
2015/04 - 2017/03 National Agriculture and Food Research Organization
2011/04 - 2015/03 National Institute of Agrobiological Sciences

Committee career (2)：

2018/04 - 現在日本薬学会構造活性相関部会幹事
2018/07 - 2018/11 つくば市役所スタートアップ戦略策定懇談会市民構成員

Awards (5)：

2020/12 - 日本財団ソーシャルイノベーションアワード優秀賞
2020/10 - JST/NEDO 大学発ベンチャー表彰アーリーエッジ賞
2017/11 - 日本薬学会構造活性相関シンポジウム 2017年度 SAR Presentation Award
2017/03 - 東京大学新領域創成科学研究科先端生命科学専攻博士論文特別奨励賞
2016/11 - スクリーニング学研究会第7回スクリーニング学研究会(東京)最優秀ポスター賞

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