Hoshino Shinichi

ホシノシンイチ | Hoshino Shinichi

Affiliation and department：
Homepage URL (1)： http://www.phar.nagoya-cu.ac.jp/hp/syk/index.html

Research field (3)： Cell biology , Pharmaceuticals - health and biochemistry , Molecular biology

Research keywords (3)： mRNA therapeutics , post transcriptional regulation of gene expression , mRNA decay

Papers (80)：

Koichi Ogami, Keima Ogawa, Shoko Sanpei, Fumito Ichikawa, Tsuyoshi Udagawa, Shin-ichi Hoshino. A Combinatorial Code for CPEB-Mediated c-myc Repression. Cells. 2023. 12. 19. 2410-2410
Koichi Ogami, Yuka Oishi, Shin-Ichi Hoshino. Protocol for analyzing intact mRNA poly(A) tail length using nanopore direct RNA sequencing. STAR protocols. 2023. 4. 2. 102340-102340
Koichi Ogami, Yuka Oishi, Kentaro Sakamoto, Mayu Okumura, Ryota Yamagishi, Takumi Inoue, Masaya Hibino, Takuto Nogimori, Natsumi Yamaguchi, Kazuya Furutachi, et al. mTOR- and LARP1-dependent regulation of TOP mRNA poly(A) tail and ribosome loading. Cell reports. 2022. 41. 4. 111548-111548
Takeru Sagae, Mariko Yokogawa, Ryoichi Sawazaki, Yuichiro Ishii, Nao Hosoda, Shin-Ichi Hoshino, Shunsuke Imai, Ichio Shimada, Masanori Osawa. Paip2A inhibits translation by competitively binding to the RNA recognition motifs of PABPC1 and promoting its dissociation from the poly(A) tail. The Journal of biological chemistry. 2022. 298. 5. 101844-101844
Hiroto Inagaki, Nao Hosoda, Shin-ichi Hoshino. DDX6 is a positive regulator of Ataxin-2/PAPD4 cytoplasmic polyadenylation machinery. Biochemical and Biophysical Research Communications. 2021. 553. 9-16

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MISC (39)：

星野真一. 夢の新薬mRNA医薬. 名市大ブックス. 2023. 14. 24-31
星野真一. mRNAの分解機構に基づいたmRNA医薬の安定化. 現代化学特集号『台頭するmRNA医薬』. 2022. 620. 38-40
尾上耕一, 星野真一. がん抑制遺伝子産物TobによるmRNA分解を介したがん抑制と学習記憶の調節. ファルマシア特集号『RNA研究が切り開く薬学フロンティア』. 2015. 51. 1. 27-31
尾上耕一, 星野真一. mRNA分解研究と創薬. 日本薬理学雑誌. 2010. 136. 150-154
Shin-ichi Hoshino. Initiation mechanism of mRNA decay. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2009. 54. 16 Suppl. 2066-2072

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Patents (4)：

Professional career (1)：

Association Membership(s) (4)：

THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE BIOCHEMICAL SOCIETY , THE RNA SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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