Art

J-GLOBAL ID：201702210714911671   Reference number：17A0655932

Soft palatal melanosis, a simple predictor for neoplasia in the upper aerodigestive tract in Japanese alcoholic men

アルコール依存症日本人男性の上部気道消化管腫瘍のための簡易予測因子である軟口蓋メラノーシス

Author (9)： Hirata Kenro (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan) ,  Yokoyama Akira (National Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan) ,  Nakamura Rieko (Department of Surgery, Keio University School of Medicine, Tokyo, Japan) ,  Omori Tai (Endoscopy Center, Kawasaki Municipal Ida Hospital, Kawasaki, Japan) ,  Kawakubo Hirofumi (Department of Surgery, Keio University School of Medicine, Tokyo, Japan) ,  Mizukami Takeshi (National Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan) ,  Maruyama Katsuya (National Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan) ,  Kanai Takanori (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan) ,  Yokoyama Tetsuji (Department of Health Promotion, National Institute of Public Health, Wako, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 108  Issue： 5  Page： 1058-1064  Publication year： 2017 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *melanism ,...
Semi thesaurus term： aldehyde dehydrogenase 2 ,...

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Author keywords (5)： Neoplasia ,  predictive factor ,  soft palatal melanosis ,  squamous cell carcinoma ,  upper aerodigestive tract

JST classification (4)： Clinical oncology in general  (GE03010Y) ,  Tumors(=neoplasms)of digestive system  (GH04000D) ,  Skin diseases  (GF03000Q) ,  Poisoning in general  (GD06010Q)

Reference (29)：

• Yokoyama A, Mizukami T, Omori T et al. Melanosis and squamous cell neoplasms of the upper aerodigestive tract in Japanese alcoholic men. Cancer Sci 2006; 97: 905-11.
• Yokoyama A, Omori T, Yokoyama T et al. Risk of squamous cell carcinoma of the upper aerodigestive tract in cancer-free alcoholic Japanese men: an endoscopic follow-up study. Cancer Epidemiol Biomarkers Prev 2006; 15: 2209-15.
• Crabb DW, Matsumoto M, Chang D, You M. Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology. Proc Nutr Soc 2004; 63: 49-63.
• Cui R, Kamatani Y, Takahashi A et al. Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. Gastroenterology 2009; 137: 1768-75.
• Tanaka F, Yamamoto K, Suzuki S et al. Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles. Gut 2010; 59: 1457-64.

Terms in the title (9)： アルコール依存症 ,  日本人 ,  男性 ,  気道 ,  消化管腫瘍 ,  簡易 ,  予測因子 ,  軟口蓋 ,  メラノーシス