Art

J-GLOBAL ID：201702212190818488   Reference number：17A0890577

Multiple production of α,α-disubstituted amino acid derivatives through direct chemical derivatization of natural plant extracts: An apparently difficult but successful route

天然植物エキスの直接化学誘導体化を介するα,α-二置換アミノ酸誘導体の多様な生成:明らかに困難と思われたが成功した経路【Powered by NICT】

Author (7)： Tomohara Keisuke (Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan) ,  Ito Tomohiro (Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan) ,  Furusawa Kota (Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan) ,  Hasegawa Naoto (Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan) ,  Tsuge Kiyoshi (Graduate School of Science and Engineering, University of Toyama, 3190 Gofuku, Toyama 930-8555, Japan) ,  Kato Atsushi (Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan) ,  Adachi Isao (Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 58  Issue： 32  Page： 3143-3147  Publication year： Aug. 09, 2017 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Natural plant extracts are ric...

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Thesaurus term： derivatization ,  *amino acid ,  natural material ,  extraction liquid ,  *urea compound ,  *nitrogen heterocyclic compound ,  Imidazoles ,  *Hydantoins ,  Plant Extracts ,  aromatic ketone ,  phenolic compound ,  phenol ether ,  hydroxy ketone
Semi thesaurus term： *amino acid derivatives ,  Imidazoles ,  *Hydantoins ,  plant extract ,  natural material

Author keywords (5)： Direct chemical derivatization ,  Natural plant extract ,  Amino acid derivative ,  Tetrasubstituted carbon ,  Bucherer-Bergs reaction

JST classification (2)： Amino acids  (CF10070V) ,  Imidazoles  (CF07083X)

Substance index (11)： Curcumenone ,  Peonol ,  4-Methyl-4-(2-hydroxy-4-methoxyphenyl)imidazolidine-2,5-dione ,  (S)-5α-[(S)-2-Hydroxyheptyl]-5-(4-hydroxy-3-methoxyphenethyl)imidazolidine-2,4-dione ,  (R)-5β-[(S)-2-Hydroxyheptyl]-5-(4-hydroxy-3-methoxyphenethyl)imidazolidine-2,4-dione ,  (S)-5α-[(S)-2-Hydroxyundecyl]-5-(4-hydroxy-3-methoxyphenethyl)imidazolidine-2,4-dione ,  (R)-5β-[(S)-2-Hydroxyundecyl]-5-(4-hydroxy-3-methoxyphenethyl)imidazolidine-2,4-dione ,  2-Oxo-4-methyl-7-methoxy-3,4-dihydro-2H-1,3-benzooxazine-4-carboxamide ,  2-Oxo-4-(4-hydroxy-3-methoxyphenethyl)-6α-pentyltetrahydro-2H-1,3-oxazine-4-carboxamide ,  (4S)-2-Oxo-4-(4-hydroxy-3-methoxyphenethyl)-6α-nonyltetrahydro-2H-1,3-oxazine-4α-carboxamide ,  (4R)-2-Oxo-4-(4-hydroxy-3-methoxyphenethyl)-6α-nonyltetrahydro-2H-1,3-oxazine-4β-carboxamide

Terms in the title (7)： 植物エキス ,  化学 ,  誘導体化 ,  置換 ,  アミノ酸誘導体 ,  成功 ,  経路