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J-GLOBAL ID：201702212891890304   Reference number：17A1410209

Elevated Serum High-Mobility Group Box-1 Protein Level Is Associated with Poor Functional Outcome in Ischemic Stroke

血清高移動度グループボックス-1蛋白質レベルの上昇は虚血性脳卒中における不良な機能的転帰と関連する

Author (8)： Tsukagawa Toshiyuki (Department of Emergency and Critical Care Center, Nagoya Daini Red Cross Hospital, Nagoya, Japan) ,  Katsumata Ryu (Department of Neurology, Showa University School of Medicine, Tokyo, Japan) ,  Fujita Mitsugu (Department of Microbiology, Kindai University Faculty of Medicine, Osaka, Japan) ,  Yasui Keizo (Department of Neurology, Nagoya Daini Red Cross Hospital, Nagoya, Japan) ,  Akhoon Cassim (Department of Acute General Medicine, Oxford University Hospitals NHS Trust, Oxford, UK) ,  Ono Kenjiro (Department of Neurology, Showa University School of Medicine, Tokyo, Japan) ,  Dohi Kenji (Department of Emergency and Critical Care Medicine, Showa University School of Medicine, Tokyo, Japan) ,  Aruga Toru (Japan Organization of Occupational Health and Safety, Tokyo, Japan)
Material： Journal of Stroke & Cerebrovascular Diseases  (J Stroke Cerebrovasc Dis)
Volume： 26  Issue： 10  Page： 2404-2411  Publication year： Oct. 2017 
JST Material Number： W1420A  ISSN： 1052-3057  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： evaluation criterion ,...
Semi thesaurus term： serodiagnosis ,...

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Author keywords (5)： Prognosis ,  cerebral ischemia ,  HMGB proteins ,  inflammation ,  cerebral infarction

JST classification (1)： Neurologic diagnosis  (GN02000H)

Reference (39)：

• Moskowitz, M.A., Lo, E.H., Iadecola, C. The science of stroke: mechanisms in search of treatments. Neuron. 2010;67:181-198.
• Lo, E.H. Degeneration and repair in central nervous system disease. Nat Med. 2010;16:1205-1209.
• Jordan, J., Segura, T., Brea, D. et al, Inflammation as therapeutic objective in stroke. Curr Pharm Des. 2008;14:3549-3564.
• Hacke, W., Kaste, M., Fieschi, C. et al, Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS). JAMA. 1995;274:1017-1025.
• National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. 1995;333:1581-1587.

Terms in the title (7)： 血清 ,  高移動度 ,  グループ ,  ボックス ,  蛋白質レベル ,  虚血性脳卒中 ,  機能的転帰