Art
J-GLOBAL ID：201702215267003638
Reference number：17A0087861
UDP-glucuronosyltransferase 1A1*6 and *28 polymorphisms as indicators of initial dose level of irinotecan to reduce risk of neutropenia in patients receiving FOLFIRI for colorectal cancer
結腸直腸癌でFOLFIRI治療を受けている患者の好中球減少症のリスクを低下させるイリノテカンの初期レベルのインジケーターとしてのUDP-グルクロノシルトランスフェラーゼ1A1*6と*28多型
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Author (7)：
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Material：
Volume：
21
Issue：
4
Page：
696-703
Publication year：
Aug. 2016
JST Material Number：
L3966A
ISSN：
1341-9625
Document type：
Article
Article type：
原著論文
Country of issue：
Germany, Federal Republic of (DEU)
Language：
ENGLISH (EN)
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Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
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Author keywords (5)：
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JST classification (2)：
JST classification
Category name(code) classified by JST.
Tumors(=neoplasms)of digestive system
, Drug therapy(=pharmacotherapy)for tumors
Substance index (1)：
Substance index
Chemical Substance indexed to the Article.
Reference (20)：
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Douillard JY, Cunningham D, Roth AD et al (2000) Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 355:1041-1047
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Tournigand C, André T, Achille E et al (2004) FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 22:229-237
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Kono A, Hara Y (1991) Conversion of CPT-11 into SN-38 in human tissues. Gan To Kagaku Ryoho 18:2175-2178 (in Japanese)
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Kawato Y, Aonuma M, Matsumoto K et al (1991) Production of SN-38, a main metabolite of the camptothecin derivative CPT-11, and its species and tissue specificities. Drug Metab Pharmacokinet 6:899-907 (in Japanese)
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Rivory LP, Robert J (1995) Identification and kinetics of a beta-glucuronide metabolite of SN-38 in human plasma after administration of the camptothecin derivative irinotecan. Cancer Chemother Pharmacol 36:176-179
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Terms in the title (12)：
Terms in the title
Keywords automatically extracted from the title.
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