Art
J-GLOBAL ID:201702216295585037   Reference number:17A1410149

A novel prostanoid EP1 receptor antagonist, ONO-8539, reduces acid-induced heartburn symptoms in healthy male volunteers: a randomized clinical trial

新規プロスタノイドEP1受容体アンタゴニストONO-8539は,健常な男性被験者において酸誘発性胸焼け症状を軽減する:無作為化臨床試験
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Material:
Volume: 52  Issue: 10  Page: 1081-1089  Publication year: 2017 
JST Material Number: Z0748A  ISSN: 0944-1174  Document type: Article
Article type: 原著論文  Country of issue: Germany, Federal Republic of (DEU)  Language: ENGLISH (EN)
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Category name(code) classified by JST.
Drug therapy(=pharmacotherapy)for digestive system diseases  ,  Clinical application of drugs acting on digestive system 
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Reference (51):
  • Dent J, El-Serag HB, Wallander MA, et al. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2005;54:710-7.
  • Wiklund I, Carlsson J, Vakil N. Gastroesophageal reflux symptoms and well-being in a random sample of the general population of a Swedish community. Am J Gastroenterol. 2006;101:18-28.
  • Wiklund I. Review of the quality of life and burden of illness in gastroesophageal reflux disease. Dig Dis. 2004;22:108-14.
  • Dean BB, Gano AD Jr, Knight K, et al. Effectiveness of proton pump inhibitors in nonerosive reflux disease. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2004;2:656-64.
  • Holloway RH, Dent J, Narielvala F, et al. Relation between oesophageal acid exposure and healing of oesophagitis with omeprazole in patients with severe reflux oesophagitis. Gut. 1996;38:649-54.
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