Art

J-GLOBAL ID：201702216376298560   Reference number：17A1818237

Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Na_v1.1 to Na_v1.7)

テトロドトキシンの異なった結合性と電圧感受性ナトリウムチャンネルサブタイプ(Na_v1 1Na_v1 7)へのその誘導体【Powered by NICT】

Author (14)： Tsukamoto Tadaaki (Graduate School of Agricultural Science, Tohoku University, Sendai, Japan) ,  Chiba Yukie (Graduate School of Agricultural Science, Tohoku University, Sendai, Japan) ,  Wakamori Minoru (Graduate School of Dentistry, Tohoku University, Sendai, Japan) ,  Yamada Tomoshi (Graduate School of Agricultural Science, Tohoku University, Sendai, Japan) ,  Tsunogae Shunsuke (Graduate School of Agricultural Science, Tohoku University, Sendai, Japan) ,  Cho Yuko (Graduate School of Agricultural Science, Tohoku University, Sendai, Japan) ,  Sakakibara Ryo (Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan) ,  Imazu Takuya (Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan) ,  Tokoro Shouta (Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan) ,  Satake Yoshiki (Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan) ,  Adachi Masaatsu (Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan) ,  Nishikawa Toshio (Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan) ,  Yotsu-Yamashita Mari (Graduate School of Agricultural Science, Tohoku University, Sendai, Japan) ,  Konoki Keiichi (Graduate School of Agricultural Science, Tohoku University, Sendai, Japan)
Material： British Journal of Pharmacology  (Br J Pharmacol)
Volume： 174  Issue： 21  Page： 3881-3892  Publication year： 2017 
JST Material Number： B0334A  ISSN： 0007-1188  CODEN： BJPCB  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： BACKGROUND AND PURPOSE: The de...

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Thesaurus term： therapy ,  amino acid residue ,  analogical material ,  binding site ,  *connectivity ,  *sodium channel ,  *sensitivity ,  patch-clamp ,  crystal structure ,  human(primates) ,  Mammalia ,  alicyclic compound ,  nitrogen heterocyclic compound ,  oxygen heterocyclic compound ,  onium compound ,  bridged compound ,  zwitterion ,  polyol
Semi thesaurus term： 結合親和性 ,  特異性 ,  *サブタイプ , 【Automatic Indexing@JST】

JST classification (4)： Basic research of psychotropic drugs  (GW03100Y) ,  Basic research of parasympathetics  (GW05032S) ,  Transport of cell membrane  (EF04020R) ,  Receptors on cell membrane  (EF04030C)

Substance index (1)： Tetrodotoxin

Terms in the title (4)： テトロドトキシン ,  結合性 ,  感受性 ,  誘導体