Art

J-GLOBAL ID：201702217850981476   Reference number：17A0203699

Design,synthesis and biological evaluation of pyrrolo-pyridine derivatives as HIV-1 integrase inhibitors

ピロール類合成酵素阻害剤の設計,合成および生物活性研究【JST・京大機械翻訳】

Author (6)： Ju Lun (College of Life Science and Bioengineering,Beijing University of Technology) ,  Mao Zhijie (College of Life Science and Bioengineering,Beijing University of Technology) ,  Wang Xiaoli (College of Life Science and Bioengineering,Beijing University of Technology) ,  Liu Wei (College of Life Science and Bioengineering,Beijing University of Technology) ,  Zeng Chengchu (College of Life Science and Bioengineering,Beijing University of Technology) ,  Hu Liming (College of Life Science and Bioengineering,Beijing University of Technology)
Material： Guoji Yaoxue Yanjiu Zazhi
Volume： 43  Issue： 5  Page： 940-946  Publication year： 2016 
JST Material Number： C2687A  ISSN： 1674-0440  Document type： Article
Article type： 原著論文  Country of issue： China (CHN)  Language： CHINESE (ZH)

Abstract/Point： Objective To design and synthe...

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Thesaurus term： optimization ,  NMR ,  integrase ,  binding energy ,  *biological activity ,  total synthesis ,  *enzyme inhibitor
Semi thesaurus term： 構造活性 ,  阻害活性 ,  分子ドッキング ,  *阻害剤 ,  *ピロール類 , 【Automatic Indexing@JST】

Author keywords (3)： human immunodeficiency virus(HIV) ,  integrase ,  pyrrolopyridine

JST classification (2)： Physicochemical pharmacy in general  (GV01010J) ,  Structure-activity relationship of drugs  (GV01050B)

Terms in the title (5)： ピロール類 ,  酵素阻害剤 ,  設計 ,  生物活性 ,  研究