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J-GLOBAL ID：201702217854983458   Reference number：17A0566008

A Clinical Study on Administration of Opioid Antagonists in Terminal Cancer Patients: 7 Patients Receiving Opioid Antagonists Following Opioids among 2443 Terminal Cancer Patients Receiving Opioids

末期癌患者におけるオピオイド拮抗薬の投与に関する臨床試験:オピオイドを受けた末期癌患者2443人の中でのオピオイド後にオピオイド拮抗薬を受けた患者7人

Author (11)： Uekuzu Yoshihiro (Department of Pharmacy, Fujita Health University Nanakuri Memorial Hospital) ,  Uekuzu Yoshihiro (Department of Surgery and Palliative Medicine, School of Medicine, Fujita Health University) ,  Higashiguchi Takashi (Department of Surgery and Palliative Medicine, School of Medicine, Fujita Health University) ,  Futamura Akihiko (Department of Pharmacy, Fujita Health University Nanakuri Memorial Hospital) ,  Futamura Akihiko (Department of Surgery and Palliative Medicine, School of Medicine, Fujita Health University) ,  Ito Akihiro (Department of Surgery and Palliative Medicine, School of Medicine, Fujita Health University) ,  Mori Naoharu (Department of Surgery and Palliative Medicine, School of Medicine, Fujita Health University) ,  Murai Miyo (Department of Surgery and Palliative Medicine, School of Medicine, Fujita Health University) ,  Ohara Hiroshi (Department of Surgery and Palliative Medicine, School of Medicine, Fujita Health University) ,  Awa Hiroko (Department of Surgery and Palliative Medicine, School of Medicine, Fujita Health University) ,  Chihara Takeshi (Division of Biochemistry, Fujita Memorial Nanakuri Institute, Fujita Health University)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 40  Issue： 3  Page： 278-283(J-STAGE)  Publication year： 2017 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： Depression respiratory ,...

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Author keywords (10)： terminal cancer patient ,  opioid antagonist ,  respiratory depression ,  morphine ,  opioid ,  terminal cancer patient ,  opioid antagonist ,  respiratory depression ,  morphine ,  opioid

JST classification (1)： Clinical oncology in general  (GE03010Y)

Reference (37)：

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• 2) Morita T, Tsunoda J, Inoue S, Chihara S. Contributing factors to physical symptoms in terminally-ill cancer patients. J. Pain Symptom Manage., 18, 338-346 (1999).
• 3) Qaseem A, Snow V, Shekelle P, Casey DE Jr, Cross JT Jr, Owens DK, Clinical Efficacy Assessment Subcommittee of the American College of Physicians, Dallas P, Dolan NC, Forciea MA, Halasyamani L, Hopkins RH Jr, Shekelle P. Evidence-based interventions to improve the palliative care of pain, dyspnea, and depression at the end of life: a clinical practice guideline from the American College of Physicians. Ann. Intern. Med., 148, 141-146 (2008).
• 4) Japanese Society for Palliative Medicine. <i>Clinical guidelines for Cancer Pain Management Second Edition</i>. Kanehara & Co., LTD., Tokyo, pp. 60-63 (2014).
• 5) Iwase S, Murakami T, Umenai M, Saitou Y, Nakagawa K. Morphine metabolite activity-Report on pancreatic cancer patient under terminal care that developed respiratory depression with a low dose of morphine-. Rinsho Iyaku, 20, 977-981 (2004).

Terms in the title (7)： 末期 ,  癌患者 ,  オピオイド拮抗薬 ,  投与 ,  臨床試験 ,  オピオイド ,  患者