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J-GLOBAL ID：201702219234102848   Reference number：17A0440573

CpG site DNA methylation patterns reveal a novel regulatory element in the mouse prion protein gene

CpG部位DNAメチル化パターンはマウスプリオン蛋白質遺伝子における新規制御因子を明らかにする

Author (5)： DALAI Wuyun (Laboratory of Microbiology and Immunology, Graduate School of Agricultural Science, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, Japan) ,  MATSUO Eiko (Laboratory of Microbiology and Immunology, Graduate School of Agricultural Science, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, Japan) ,  TAKEYAMA Natsumi (Research Department, Nippon Institute for Biological Science, 9-2221-1 Shinmachi, Ome, Tokyo 198-0024, Japan) ,  KAWANO Junichi (Laboratory of Microbiology and Immunology, Graduate School of Agricultural Science, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, Japan) ,  SAEKI Keiichi (Laboratory of Microbiology and Immunology, Graduate School of Agricultural Science, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, Japan)
Material： Journal of Veterinary Medical Science (Web)
Volume： 79  Issue： 1  Page： 100-107(J-STAGE)  Publication year： 2017 
JST Material Number： U1094A  ISSN： 1347-7439  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Methylation ,...
Semi thesaurus term： genetic regulation

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Author keywords (4)： epigenetics ,  DNA methylation ,  prion ,  prion protein gene

JST classification (2)： Animal biochemistry  (EJ01050P) ,  Structure and chemistry of genes  (EC02020U)

Reference (31)：

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• 3. Bendheim, P. E., Brown, H. R., Rudelli, R. D., Scala, L. J., Goller, N. L., Wen, G. Y., Kascsak, R. J., Cashman, N. R. and Bolton, D. C. 1992. Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology 42: 149-156.
• 4. Bird, A. 2007. Perceptions of epigenetics. Nature 447: 396-398.
• 5. Büeler, H., Aguzzi, A., Sailer, A., Greiner, R. A., Autenried, P., Aguet, M. and Weissmann, C. 1993. Mice devoid of PrP are resistant to scrapie. Cell 73: 1339-1347.

Terms in the title (5)： CPG ,  DNAメチル化 ,  マウス ,  プリオン蛋白質遺伝子 ,  制御因子