Art

J-GLOBAL ID：201702220352524247   Reference number：17A1020824

PEGylation of a TLR2-agonist-based vaccine delivery system improves antigen trafficking and the magnitude of ensuing antibody and CD8⁺ T cell responses

TLR2アゴニストベースワクチンデリバリー系のPEG化は抗原輸送とその後の抗体およびCD8~+T細胞応答の大きさを改善する【Powered by NICT】

Author (17)： Sekiya Toshiki (Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, 3000, Australia) ,  Yamagishi Junya (Research Center for Zoonosis Control, Hokkaido University, Sapporo, 001-0020, Japan) ,  Yamagishi Junya (Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, 001-0020, Japan) ,  Gray John Henry V. (Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, 3000, Australia) ,  Whitney Paul G. (Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, 3000, Australia) ,  Martinelli Axel (Research Center for Zoonosis Control, Hokkaido University, Sapporo, 001-0020, Japan) ,  Martinelli Axel (Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, 001-0020, Japan) ,  Zeng Weiguang (Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, 3000, Australia) ,  Wong Chinn Yi (Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, 3000, Australia) ,  Sugimoto Chihiro (Research Center for Zoonosis Control, Hokkaido University, Sapporo, 001-0020, Japan) ,  Sugimoto Chihiro (Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, 001-0020, Japan) ,  Jackson David C. (Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, 3000, Australia) ,  Jackson David C. (Research Center for Zoonosis Control, Hokkaido University, Sapporo, 001-0020, Japan) ,  Jackson David C. (Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, 001-0020, Japan) ,  Chua Brendon Y. (Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, 3000, Australia) ,  Chua Brendon Y. (Research Center for Zoonosis Control, Hokkaido University, Sapporo, 001-0020, Japan) ,  Chua Brendon Y. (Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, 001-0020, Japan)
Material： Biomaterials
Volume： 137  Page： 61-72  Publication year： 2017 
JST Material Number： C0964B  ISSN： 0142-9612  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： The lipopeptide R₄P...

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Thesaurus term： immunogenicity ,  receptor ,  *T cell ,  *vaccine ,  *antibody ,  adjuvant ,  dendritic cell ,  in vitro experiment ,  *antigen ,  Antigen Presentation ,  complex (substance) ,  pathogen ,  gene ,  Lipopeptides ,  *polyethylene glycolylation

Author keywords (5)： CD8 T cells ,  Antibody ,  TLR2 ,  Polyethylene glycol ,  Antigen trafficking

JST classification (3)： Immunological reaction in general  (ED03010T) ,  Basic biopharmacy  (GY01021U) ,  Medical materials  (GA05040H)

Terms in the title (4)： TLR2 ,  PEG化 ,  抗原輸送 ,  抗体