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J-GLOBAL ID：201702221253659137   Reference number：17A0650236

The role of the ALK receptor in cancer biology

癌生物学におけるALK受容体の役割

Author (2)： HALLBERG B. (Univ. of Gothenburg, Gothenburg, SWE) ,  PALMER R. H. (Univ. of Gothenburg, Gothenburg, SWE)
Material： Annals of Oncology  (Ann Oncol)
Volume： 27  Issue： Supplement 3  Page： iii4-iii15  Publication year： 2016 
JST Material Number： W0107A  ISSN： 0923-7534  CODEN： ANONE2  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *receptor tyrosine kinase ,...
Semi thesaurus term： Tyrosine kinase receptor ,...

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JST classification (3)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Tumors(=neoplasms)of respiratory system  (GI04000G) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (2)： Crizotinib ,  Ceritinib

Reference (142)：

• Morris SW, Kirstein MN, Valentine MB et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 1994; 263: 1281-1284.
• Shiota M, Fujimoto J, Semba T et al. Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3. Oncogene 1994; 9: 1567-1574.
• Iwahara T, Fujimoto J, Wen D et al. Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system. Oncogene 1997; 14: 439-449.
• Morris SW, Naeve C, Mathew P et al. ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK). Oncogene 1997; 14: 2175-2188.
• Loren CE, Scully A, Grabbe C et al. Identification and characterization of DAlk: a novel Drosophila melanogaster RTK which drives ERK activation in vivo. Genes Cells 2001; 6: 531-544.

Terms in the title (4)： 癌生物学 ,  ALK ,  受容体 ,  役割