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J-GLOBAL ID：201702221863740018   Reference number：17A0568814

Involvement of DNA methylation in regulating rat Prop1 gene expression during pituitary organogenesis

下垂体器官形成中のラットProp1遺伝子発現の調節におけるDNAメチル化の介入

Author (12)： NISHIHARA Hiroto (Laboratory of Molecular Biology and Gene Regulation, Division of Life Science, Graduate School of Agriculture, Meiji University, Kanagawa 214-8571, Japan) ,  YOSHIDA Saishu (Laboratory of Molecular Biology and Gene Regulation, Division of Life Science, Graduate School of Agriculture, Meiji University, Kanagawa 214-8571, Japan) ,  YOSHIDA Saishu (Institute for Endocrinology, Meiji University, Kanagawa 214-8571, Japan) ,  KANNO Naoko (Laboratory of Molecular Biology and Gene Regulation, Division of Life Science, Graduate School of Agriculture, Meiji University, Kanagawa 214-8571, Japan) ,  NISHIMURA Naoto (Laboratory of Molecular Biology and Gene Regulation, Division of Life Science, Graduate School of Agriculture, Meiji University, Kanagawa 214-8571, Japan) ,  UEHARU Hiroki (Laboratory of Molecular Biology and Gene Regulation, Division of Life Science, Graduate School of Agriculture, Meiji University, Kanagawa 214-8571, Japan) ,  OHGANE Jun (Institute for Endocrinology, Meiji University, Kanagawa 214-8571, Japan) ,  OHGANE Jun (School of Agriculture, Meiji University, Kanagawa 214-8571, Japan) ,  KATO Takako (Institute for Endocrinology, Meiji University, Kanagawa 214-8571, Japan) ,  KATO Yukio (Laboratory of Molecular Biology and Gene Regulation, Division of Life Science, Graduate School of Agriculture, Meiji University, Kanagawa 214-8571, Japan) ,  KATO Yukio (Institute for Endocrinology, Meiji University, Kanagawa 214-8571, Japan) ,  KATO Yukio (School of Agriculture, Meiji University, Kanagawa 214-8571, Japan)
Material： Journal of Reproduction and Development  (J Reprod Dev)
Volume： 63  Issue： 1  Page： 37-44(J-STAGE)  Publication year： 2017 
JST Material Number： F0766A  ISSN： 0916-8818  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *pituitary gland ,...
Semi thesaurus term： CpG ,...

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Author keywords (5)： DNA methylation ,  Organogenesis ,  Pituitary ,  PROP1 ,  Rat

JST classification (2)： Physiology and anatomy of endocrine system  (EJ08000J) ,  Gene expression  (EC02040Q)

Reference (21)：

• 1. Sornson MW, Wu W, Dasen JS, Flynn SE, Norman DJ, OConnell SM, Gukovsky I, Carrière C, Ryan AK, Miller AP, Zuo L, Gleiberman AS, Andersen B, Beamer WG, Rosenfeld MG. Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature 1996; 384: 327-333.
• 2. Ward RD, Raetzman LT, Suh H, Stone BM, Nasonkin IO, Camper SA. Role of PROP1 in pituitary gland growth. Mol Endocrinol 2005; 19: 698-710.
• 3. Cushman LJ, Watkins-Chow DE, Brinkmeier ML, Raetzman LT, Radak AL, Lloyd RV, Camper SA. Persistent Prop1 expression delays gonadotrope differentiation and enhances pituitary tumor susceptibility. Hum Mol Genet 2001; 10: 1141-1153.
• 4. Raetzman LT, Ward R, Camper SA. Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia. Development 2002; 129: 4229-4239.
• 5. Chen J, Hersmus N, Van Duppen V, Caesens P, Denef C, Vankelecom H. The adult pituitary contains a cell population displaying stem/progenitor cell and early embryonic characteristics. Endocrinology 2005; 146: 3985-3998.

Terms in the title (7)： 下垂体 ,  器官形成 ,  ラット ,  PROP1 ,  遺伝子発現 ,  調節 ,  DNAメチル化