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J-GLOBAL ID：201702222514215156   Reference number：17A1972311

Organelle Specific O-Glycosylation Drives MMP14 Activation, Tumor Growth, and Metastasis

細胞小器官特異的O-グリコシル化MMP14の活性化,腫瘍の増殖,および転移を促進する【Powered by NICT】

Author (11)： Nguyen Anh Tuan (Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore) ,  Chia Joanne (Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore) ,  Ros Manon (Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore) ,  Hui Kam Man (Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore) ,  Hui Kam Man (Department of Biochemistry, National University of Singapore, 21 Lower Kent Ridge Road, Singapore 119077, Singapore) ,  Hui Kam Man (Division of Cellular and Molecular Research, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 169610, Singapore) ,  Hui Kam Man (Duke-NUS Graduate Medical School, Singapore, 8 College Road, Singapore 169857, Singapore) ,  Saltel Frederic (INSERM, U1053 Bordeaux Research In Translational Oncology, BaRITOn, 33000 Bordeaux, France) ,  Saltel Frederic (University of Bordeaux, U1053 Bordeaux Research In Translational Oncology, BaRITOn, 33000 Bordeaux, France) ,  Bard Frederic (Institute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore) ,  Bard Frederic (Department of Biochemistry, National University of Singapore, 21 Lower Kent Ridge Road, Singapore 119077, Singapore)
Material： Cancer Cell
Volume： 32  Issue： 5  Page： 639-653.e6  Publication year： 2017 
JST Material Number： W1844A  ISSN： 1535-6108  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Cancers grow within tissues th...

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Thesaurus term： in vitro experiment ,  Golgi body ,  human(primates) ,  endoplasmic reticulum ,  *tumor ,  liver tumor ,  cell proliferation ,  glycosyltransferase ,  matrix metalloproteinase ,  *glycosylation
Semi thesaurus term： 腫瘍のひろがり ,  細胞表面蛋白質 ,  分子機構 ,  *マトリックスメタロプロテイナーゼ14 ,  *O-グリコシル化 , 【Automatic Indexing@JST】

Author keywords (10)： O-glycosylation ,  GALNTs ,  membrane trafficking ,  MT1-MMP ,  MMP14 ,  invasion ,  metastasis ,  tumor growth ,  Tn antigen ,  GALA

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (7)： 細胞小器官 ,  O-グリコシル化 ,  MMP14 ,  活性化 ,  腫瘍 ,  増殖 ,  促進