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J-GLOBAL ID：201702223721540349   Reference number：17A1493006

The Circular RNA Interacts with STAT3, Increasing Its Nuclear Translocation and Wound Repair by Modulating Dnmt3a and miR-17 Function

環状RNAはSTAT3と相互作用し,調節Dnmt3aとmiR-17機能によるその核移行および創傷修復を増加【Powered by NICT】

Author (20)： Yang Zhen-Guo (Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada) ,  Yang Zhen-Guo (Institute of Animal Nutrition, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu, 611130 Sichuan, China) ,  Yang Zhen-Guo (Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada) ,  Awan Faryal Mehwish (Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada) ,  Awan Faryal Mehwish (Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada) ,  Awan Faryal Mehwish (Atta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), H-12 Islamabad, Pakistan) ,  Du William W. (Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada) ,  Du William W. (Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada) ,  Zeng Yan (Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada) ,  Zeng Yan (Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada) ,  Zeng Yan (Department of Cardiovascular Medicine, Second Xiangya Hospital of Central South University, 139 Middle Ren-Min Road, Changsha, 410011 Hunan, China) ,  Lyu Juanjuan (Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada) ,  Lyu Juanjuan (Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada) ,  Wu De (Institute of Animal Nutrition, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu, 611130 Sichuan, China) ,  Gupta Shaan (Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada) ,  Gupta Shaan (Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada) ,  Yang Weining (Institute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada) ,  Yang Burton B. (Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada) ,  Yang Burton B. (Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada) ,  Yang Burton B. (Institute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada)
Material： Molecular Therapy  (Mol Ther)
Volume： 25  Issue： 9  Page： 2062-2074  Publication year： 2017 
JST Material Number： W1762A  ISSN： 1525-0016  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Delayed or impaired wound heal...

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Thesaurus term： *interaction ,  affinity ,  *Wound Healing ,  fibronectin ,  patient ,  Cell Adhesion ,  healing ,  promoter (genetics) ,  Diabetes Mellitus ,  Methylation ,  Atherosclerosis ,  MicroRNAs ,  *miR-17 ,  *DNA methyltransferase 3a ,  *RNA, Circular ,  cell junction ,  binding and coupling

Author keywords (6)： circular RNA ,  circ-Amotl1 ,  Stat3 ,  Dnmt3a ,  wound healing ,  circRNA

JST classification (2)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Basic medicine on cardiovascular system  (GJ01020K)

Terms in the title (8)： 環状RNA ,  STAT3 ,  相互作用 ,  調節 ,  Dnmt3a ,  miR-17 ,  核移行 ,  創傷修復