Art

J-GLOBAL ID：201702225794335236   Reference number：17A1511251

Differential Mechanisms for SHP2 Binding and Activation Are Exploited by Geographically Distinct Helicobacter pylori CagA Oncoproteins

SHP2結合と活性化のための異なる機構は地理的に異なるHelicobacter pylori CagA癌蛋白質による活用である【Powered by NICT】

Author (13)： Hayashi Takeru (Department of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Senda Miki (Structural Biology Research Center, Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba 305-0801, Japan) ,  Suzuki Nobuhiro (Structural Biology Research Center, Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba 305-0801, Japan) ,  Nishikawa Hiroko (Department of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Nishikawa Hiroko (Max Planck-The University of Tokyo Center for Integrative Inflammology, Tokyo 113-0033, Japan) ,  Ben Chi (Department of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Tang Chao (Department of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Nagase Lisa (Structural Biology Research Center, Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba 305-0801, Japan) ,  Inoue Kaori (Department of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Senda Toshiya (Structural Biology Research Center, Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba 305-0801, Japan) ,  Senda Toshiya (Department of Materials Structure Science, School of High Energy Accelerator Science, The Graduate University of Advanced Studies, Tsukuba 305-0801, Japan) ,  Hatakeyama Masanori (Department of Microbiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan) ,  Hatakeyama Masanori (Max Planck-The University of Tokyo Center for Integrative Inflammology, Tokyo 113-0033, Japan)
Material： Cell Reports
Volume： 20  Issue： 12  Page： 2876-2890  Publication year： 2017 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Helicobacter pylori East Asian...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=17A1511251&from=J-GLOBAL&jstjournalNo=W3124A") }}

Thesaurus term： *Helicobacter pylori ,  phosphatase ,  *oncoprotein ,  interaction ,  stomach tumor ,  affinity ,  enzyme activity ,  East Asia ,  carcinogenicity ,  SH2 domain ,  Phosphopeptides ,  tyrosine phosphorylation ,  *CagA ,  *SHP2 ,  *microorganism ,  *Spiral bacteria

Author keywords (8)： Helicobacter pylori ,  East Asian CagA ,  Western CagA ,  SHP2 ,  EPIYA motif ,  allosteric regulation ,  SH2 domain ,  gastric cancer

JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Carcinogenic mechanisms and factors  (GE02020C)

Substance index (1)： Phosphotyrosine

Terms in the title (7)： SHP2 ,  活性化 ,  地理 ,  Helicobacter ,  CagA ,  癌蛋白質 ,  活用