Art

J-GLOBAL ID：201702225904128198   Reference number：17A1236522

Identification of novel variants in HLA class II region related to HLA DPB1 expression and disease progression in patients with chronic hepatitis C

C型慢性肝炎患者におけるHLA DPB1発現と疾患進行に関連したHLAクラスII領域における新規変異体の同定【Powered by NICT】

Author (15)： Hiramatsu Katsushi (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan) ,  Matsuda Hidetaka (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan) ,  Nemoto Tomoyuki (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan) ,  Nosaka Takuto (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan) ,  Saito Yasushi (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan) ,  Naito Tatsushi (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan) ,  Takahashi Kazuto (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan) ,  Ofuji Kazuya (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan) ,  Ohtani Masahiro (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan) ,  Suto Hiroyuki (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan) ,  Yasuda Toshihiro (Faculty of Medical Sciences, Division of Medical Genetics and Biochemistry, University of Fukui, Fukui, Japan) ,  Hida Yukio (Faculty of Medical Sciences, Department of Clinical Laboratories, University of Fukui, Fukui, Japan) ,  Kimura Hideki (Faculty of Medical Sciences, Department of Clinical Laboratories, University of Fukui, Fukui, Japan) ,  Soya Yoshihiro (Tsuruga Institute of Biotechnology, Toyobo Co., Ltd., Osaka, Japan) ,  Nakamoto Yasunari (Faculty of Medical Sciences, Second Department of Internal Medicine, University of Fukui, Fukui, Japan)
Material： Journal of Medical Virology  (J Med Virol)
Volume： 89  Issue： 9  Page： 1574-1583  Publication year： 2017 
JST Material Number： E0726B  ISSN： 0146-6615  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Recent genome-wide studies hav...

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Thesaurus term： RNA ,  gene frequency ,  *chronic hepatitis C ,  Heredity ,  infection ,  single nucleotide polymorphism ,  liver disease ,  *patient ,  Genotype ,  gene ,  analytical instrument ,  Gene Expression Profiling ,  IL28B gene ,  *HLA class II antigen ,  *HLA-DPB1 ,  population genetics

Author keywords (5)： HCV ,  HLA-class II ,  HLA-DPB1 ,  PNALT ,  SNPs

JST classification (5)： Drug therapy(=pharmacotherapy)for digestive system diseases  (GH05020G) ,  Genetic variation  (EC01030Y) ,  Infectious diseases,parasitics diseases in general.  (GD01010H) ,  Clinical application of antiviral drugs  (GW17050Z) ,  Clinical application of drugs acting on digestive system  (GW09020B)

Terms in the title (8)： C型慢性肝炎 ,  患者 ,  HLA ,  発現 ,  疾患進行 ,  HLAクラスII ,  変異体 ,  同定