Art

J-GLOBAL ID：201702228428020989   Reference number：17A1363177

Perirhinal accumulation of neuronal alpha-synuclein in a multiple system atrophy patient with dementia

認知障害を伴う多発性全身性萎縮症患者における神経型アルファ-シヌクレインの末梢への蓄積

Author (11)： Saito Mari (Division of Neurology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan) ,  Hara Makoto (Division of Neurology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan) ,  Hara Makoto (Laboratory of Structural Neuropathology, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Ebashi Momoko (Division of Neurology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan) ,  Morita Akihiko (Division of Neurology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan) ,  Okada Kyoko (Division of Morphological and Functional Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan) ,  Homma Taku (Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan) ,  Sugitani Masahiko (Division of Morphological and Functional Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan) ,  Endo Kentaro (Histology Center, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Uchihara Toshiki (Laboratory of Structural Neuropathology, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Kamei Satoshi (Division of Neurology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan)
Material： Neuropathology (Web)  (日本神経病理学会総会学術研究会プログラム・抄録集(Web))
Volume： 37  Issue： 5  Page： 431-440  Publication year： 2017 
JST Material Number： U0508A  ISSN： 1440-1789  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： agnosia ,...
Semi thesaurus term： cognition disorder ,...

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Author keywords (5)： dementia ,  Gallyas-negative ,  multiple system atrophy ,  neuronal cytoplasmic inclusions ,  perirhinal cortex

JST classification (2)： Basic neurology  (GN01020W) ,  Biological function  (EB03040U)

Reference (32)：

• Gilman S, Wenning GK, Low PA et al. Second consensus statement on the diagnosis of multiple system atrophy. Neurology 2008; 71: 670-676.
• Papp MI, Kahn JE, Lantos PL. Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome). J Neurol Sci 1989; 94: 79-100.
• Kato S, Nakamura H. Cytoplasmic argyrophilic inclusions in neurons of pontine nuclei in patients with olivopontocerebellar atrophy: immunohistochemical and ultrastructural studies. Acta Neuropathol 1990; 79: 584-594.
• O'Sullivan SS, Massey LA, Williams DR et al. Clinical outcomes of progressive supranuclear palsy and multiple system atrophy. Brain 2008; 131: 1362-1372.
• Brown RG, Lacomblez L, Landwehrmeyer BG et al. Cognitive impairment in patients with multiple system atrophy and progressive supranuclear palsy. Brain 2010; 133: 2382-2393.

Terms in the title (7)： 認知障害 ,  全身 ,  萎縮症 ,  患者 ,  神経 ,  アルファ-シヌクレイン ,  蓄積