Art

J-GLOBAL ID：201702231245062053   Reference number：17A0025190

Aptamers that bind specifically to human KPNA2 (importin-α1) and efficiently interfere with nuclear transport

ヒトKPNA2(インポーチン-α1)に特異的に結合して核輸送に効率的に干渉するアプタマー

Author (3)： YASUHARA Noriko (National Inst. of Biomedical Innovation, Osaka, JPN) ,  YASUHARA Noriko (Nihon Univ., Tokyo, JPN) ,  KUMAR Penmetcha K.R. (National Inst. of Advanced Industrial Sci. and Technol., Ibaraki, JPN)
Material： Journal of Biochemistry  (JB)
Volume： 160  Issue： 5  Page： 259-268  Publication year： Nov. 2016 
JST Material Number： W1920A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *nuclear protein ,...

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JST classification (2)： Nucleic acids in general  (EB04010U) ,  Cell physiology in general  (EF02010S)

Reference (26)：

• Yasuhara, N., Oka, M., and Yoneda, Y. (2009) The role of nuclear transport system in cell differentiation. Sem. Cell Dev. Biol. 20, 590-599
• Pumroy, R.A. and Cingolani, G. (2015) Diversification of importin-α isoforms in cellular trafficking and disease states. Biochem, J. 466, 13-28
• Mason, D.A., Stage, D.E., and Goldfarb, D.S. (2009) Evolution of the metazoan-specific importin alpha gene family. J. Mol. Evol. 68, 351-365
• Kobe, B. (1999) Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha. Nat. Struct. Biol. 6, 388-397
• Misheva, M., Kaur, G., Ngoei, K.R., Yeap, Y.Y., Ng, I.H., Wagstaff, K.M., Ng, D.C., Jans, D.A., and Bogoyevitch, M.A. (2014) Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress. Biochim. Biophys. Acta 1843, 253-264

Terms in the title (5)： ヒト ,  インポーチン-α ,  核輸送 ,  干渉 ,  アプタマー