Art

J-GLOBAL ID：201702231721289121   Reference number：17A1607373

NUP98-HOXC13 fusion gene in acute myeloid leukemia: Pediatric case

急性骨髄性白血病におけるNUP98-HOXC13融合遺伝子:小児症例

Author (6)： Goto Hironori (Department of Pediatrics, Oita University Faculty of Medicine, Yufu, Oita, Japan) ,  Kimura Makoto (Department of Pediatrics, Oita University Faculty of Medicine, Yufu, Oita, Japan) ,  Hirano Naoki (Department of Pediatrics, Oita University Faculty of Medicine, Yufu, Oita, Japan) ,  Suenobu Souichi (Department of Pediatrics, Oita University Faculty of Medicine, Yufu, Oita, Japan) ,  Suenobu Souichi (Division of General Pediatrics and Emergency Medicine, Oita University Faculty of Medicine, Yufu, Oita, Japan) ,  Ihara Kenji (Department of Pediatrics, Oita University Faculty of Medicine, Yufu, Oita, Japan)
Material： Pediatrics International (Web)  (Pediatr Int (Web))
Volume： 59  Issue： 10  Page： 1105-1106  Publication year： 2017 
JST Material Number： U0706A  ISSN： 1442-200X  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *acute myeloid leukemia ,...
Semi thesaurus term： Nup98 ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=17A1607373&from=J-GLOBAL&jstjournalNo=U0706A") }}

Author keywords (5)： acute myeloid leukemia ,  HOX ,  NUP98 ,  NUP98-HOXC13 ,  t(11;12)(p15;q13)

JST classification (3)： Clinical oncology in general  (GE03010Y) ,  Blood cell tumors(=neoplasms)  (GK04000M) ,  Research methods in genetics  (EC01020N)

Substance index (2)： Idarubicin ,  Fludarabine

Reference (5)：

• Taga T, Tomizawa D, Takahashi H, Adachi S. Acute myeloid leukemia in children: Current status and future directions. Pediatr. Int. 2016; 58: 71-80.
• Tosic N, Stojiljkovic M, Colovic N, Colovic M, Pavlovic S. Acute myeloid leukemia with NUP98-HOXC13 fusion and FLT3 internal tandem duplication mutation: Case report and literature review. Cancer Genet. Cytogenet. 2009; 193: 98-103.
• Taketani T, Taki T, Nakamura T et al. High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes. Leukemia 2010; 24: 1975-7.
• Chou WC, Chen CY, Hou HA et al. Acute myeloid leukemia bearing t(7;11)(p15;p15) is a distinct cytogenetic entity with poor outcome and a distinct mutation profile: Comparative analysis of 493 adult patients. Leukemia 2009; 23: 1303-10.
• Xu H, Valerio DG, Eisold ME et al. NUP98 fusion proteins interact with the NSL and MLL1 complexes to drive leukemogenesis. Cancer Cell 2016; 30: 863-78.

Terms in the title (5)： 急性骨髄性白血病 ,  Nup98 ,  融合遺伝子 ,  小児 ,  症例