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J-GLOBAL ID：201702232363719718   Reference number：17A1159076

Phosphorylation of clustered serine residues in the N-terminus of BPS domain negatively regulates formation of the complex between human Grb14 and insulin receptor

BPSドメインN末端のクラスター化セリン残基のリン酸化はヒトGrb14とインスリン受容体間の複合体形成を負調節する

Author (7)： TAIRA Junichi (Kyushu Inst. of Technol., Fukuoka, JPN) ,  TAIRA Junichi (Kurume Univ. School of Medicine, Fukuoka, JPN) ,  KIDA Yutaka (Kurume Univ. School of Medicine, Fukuoka, JPN) ,  INATOMI Kohei (Kyushu Inst. of Technol., Fukuoka, JPN) ,  KOMATSU Hideyuki (Kyushu Inst. of Technol., Fukuoka, JPN) ,  HIGASHIMOTO Yuichiro (Kurume Univ. School of Medicine, Fukuoka, JPN) ,  SAKAMOTO Hiroshi (Kyushu Inst. of Technol., Fukuoka, JPN)
Material： Journal of Biochemistry  (JB)
Volume： 162  Issue： 2  Page： 113-122  Publication year： Aug. 2017 
JST Material Number： W1920A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *adaptor protein ,...
Semi thesaurus term： COS7 cell ,...

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JST classification (2)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Reference (37)：

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• Kasus-Jacobi, A., Perdereau, D., Auzan, C., Clauser, E., Van Obberghen, E., Mauvais-Jarvis, F., Girard, J., and Burnol, A.F. (1998) Identification of the rat adapter Grb14 as an inhibitor of insulin actions. J. Biol. Chem. 273, 26026-26035
• Bereziat, V., Kasus-Jacobi, A., Perdereau, D., Cariou, B., Girard, J., and Burnol, A.F. (2002) Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14. J. Biol. Chem. 277, 4845-4852
• Daly, R.J., Sanderson, G.M., Janes, P.W., and Sutherland, R.L. (1996) Cloning and characterization of GRB14, a novel member of the GRB7 gene family. J. Biol. Chem. 271, 12502-12510

Terms in the title (9)： ドメイン ,  N末端 ,  クラスター化 ,  セリン残基 ,  リン酸化 ,  ヒト ,  インスリン受容体 ,  複合体 ,  調節