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J-GLOBAL ID：201702232453901377   Reference number：17A0570997

Simultaneous depletion of WRNIP1 and RAD52 restores resistance to oxidative stress

WRNIP1とRAD52の同時消失は,酸化ストレスに対する抵抗性を取り戻す。

Author (5)： Yoshimura Akari (Molecular Cell Biology Laboratory, Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University) ,  Yabe Haruna (Molecular Cell Biology Laboratory, Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University) ,  Akatani Miho (Molecular Cell Biology Laboratory, Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University) ,  Seki Masayuki (Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University) ,  Enomoto Takemi (Molecular Cell Biology Laboratory, Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University)
Material： Fundamental Toxicological Sciences (Web)  (Fundam Toxicol Sci (Web))
Volume： 4  Issue： 1  Page： 1-7(J-STAGE)  Publication year： 2017 
JST Material Number： U0596A  ISSN： 2189-115X  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *Rad52 ,...

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Author keywords (4)： WRN ,  WRNIP1 ,  RAD52 ,  H₂O₂

JST classification (3)： Gene manipulation  (EC02050B) ,  Molecular genetics in general  (EC02010J) ,  Endocrine diseases  (GL03000I)

Reference (31)：

• Baynton, K., Otterlei, M., Bjørås, M., von Kobbe, C., Bohr, V.A. and Seeberg, E. (2003): WRN interacts physically and functionally with the recombination mediator protein RAD52. J. Biol. Chem., 278, 36476-36486.
• Bianchi, J., Rudd, S.G., Jozwiakowski, S.K., Bailey, L.J., Soura, V., Taylor, E., Stevanovic, I., Green, A.J., Stracker, T.H., Lindsay, H.D. and Doherty, A.J. (2013): PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication. Mol. Cell, 52, 566-573.
• Bohr, V.A. (2005): Deficient DNA repair in the human progeroid disorder, Werner syndrome. Mutat. Res., 577, 252-259.
• Ceccaldi, R., Rondinelli, B. and D'Andrea, A.D. (2016): Repair pathway choices and consequences at the double-strand break. Trends Cell. Biol., 26, 52-64.
• Chapman, J.R., Taylor, M.R. and Boulton, S.J. (2012): Playing the end game: DNA double-strand break repair pathway choice. Mol. Cell, 47, 497-510.

Terms in the title (3)： Rad52 ,  酸化ストレス ,  抵抗性