Art
J-GLOBAL ID：201702235260170092   Reference number：17A1208010

GSK3 inhibitor AR-A014418 promotes osteogenic differentiation of human adipose-derived stem cells via ERK and mTORC2/Akt signaling pathway

GSK3阻害剤AR-A014418はERKとmTORC2/Aktシグナル伝達経路を介してヒト脂肪由来幹細胞の骨形成分化を促進する【Powered by NICT】
Author (5)：
Zhang Min

About Zhang Min

(Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China)

About Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China

, 
Zhang Ping

About Zhang Ping

(Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China)

About Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China

, 
Liu Yunsong

About Liu Yunsong

(Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China)

About Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China

, 
Zhou Yongsheng

About Zhou Yongsheng

(Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China)

About Department of Prosthodontics, Peking University School and Hospital of Stomatology, Beijing 100081, China

, 
Zhou Yongsheng

About Zhou Yongsheng

(National Engineering Lab for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, China)

About National Engineering Lab for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, China


Material：
Biochemical and Biophysical Research Communications  (BBRC)

About Biochemical and Biophysical Research Communications


Volume： 490  Issue： 2  Page： 182-188  Publication year： 2017 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
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Small molecule-based bone tiss...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
*osteogenesis

About osteogenesis

, 
siRNA

About siRNA

, 
small molecule

About small molecule

, 
*human

About human

, 
Erk1/2

About Erk1/2

, 
Bone Induction

About Bone Induction

, 
bone tissue engineering

About bone tissue engineering

, 
*adipose tissue-derived stem cell

About adipose tissue-derived stem cell

, 
*Akt/protein kinase B

About Akt/protein kinase B

, 
*Mechanistic Target of Rapamycin Complex 2

About Mechanistic Target of Rapamycin Complex 2

, 
signal transduction pathway

About signal transduction pathway

, 
*Glycogen Synthase Kinase 3

About Glycogen Synthase Kinase 3


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
骨欠損

About 骨欠損

, 
伝達経路

About 伝達経路

, 
*阻害剤

About 阻害剤

, 
*グリコーゲンシンターゼキナーゼ3

About グリコーゲンシンターゼキナーゼ3

, 【Automatic Indexing@JST】
Author keywords (6)：
AR-A014418

About AR-A014418

, 
Human adipose-derived stem cells (hASCs)

About Human adipose-derived stem cells (hASCs)

, 
Osteogenic differentiation

About Osteogenic differentiation

, 
GSK3

About GSK3

, 
ERK1/2

About ERK1/2

, 
RICTOR

About RICTOR

JST classification (1)：
JST classification
Category name(code) classified by JST.
Cell physiology in general 
(EF02010S)

About Cell physiology in general

Substance index (1)：
Substance index
Chemical Substance indexed to the Article.
AR-A014418

About AR-A014418

Terms in the title (11)：
Terms in the title
Keywords automatically extracted from the title.
GSK3

About GSK3

, 
阻害剤

About 阻害剤

, 
AR-A014418

About AR-A014418

, 
ERK

About ERK

, 
mTORC2

About mTORC2

, 
Akt

About Akt

, 
シグナル伝達経路

About シグナル伝達経路

, 
ヒト

About ヒト

, 
脂肪由来幹細胞

About 脂肪由来幹細胞

, 
骨形成分化

About 骨形成分化

, 
促進

About 促進


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