Art

J-GLOBAL ID：201702236960023335   Reference number：17A0519274

IL-22/IL-22R1 signaling regulates the pathophysiology of chronic rhinosinusitis with nasal polyps via alteration of MUC1 expression

IL-22/IL-22R1シグナル伝達はMUC1発現変化を介して鼻ポリープ合併慢性副鼻腔炎病態を調節する

Author (16)： Noyama Yasuyuki (Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Okano Mitsuhiro (Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Fujiwara Tazuko (Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Kariya Shin (Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Higaki Takaya (Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Haruna Takenori (Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Makihara Sei-ichiro (Department of Otorhinolaryngology, Kagawa Rosai Hospital) ,  Kanai Kengo (Department of Otorhinolaryngology, Kagawa Rosai Hospital, Marugame, Japan) ,  Koyama Takahisa (Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Taniguchi Masami (Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital) ,  Ishitoya Jun-ichi (Ishitoya ENT Clinic) ,  Kanda Akira (Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University) ,  Kobayashi Yoshiki (Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University) ,  Asako Mikiya (Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University) ,  Tomoda Koichi (Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University) ,  Nishizaki Kazunori (Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences)
Material： Allergology International  (Allergol Int)
Volume： 66  Issue： 1  Page： 42-51(J-STAGE)  Publication year： 2017 
JST Material Number： L6446A  ISSN： 1323-8930  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： nasal polyp ,...
Semi thesaurus term： Chronic sinusitis ,...

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Author keywords (10)： Chronic rhinosinusitis with nasal polyps ,  Exotoxins ,  IL-22 ,  MUC1 ,  Staphylococcus aureus ,  Chronic rhinosinusitis with nasal polyps ,  Exotoxins ,  IL-22 ,  MUC1 ,  Staphylococcus aureus

JST classification (2)： Diseases of ear,nose,pharynx and larynx  (GQ03000X) ,  Immunological reaction in general  (ED03010T)

Reference (32)：

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• 4. Akdis M, Palomares O, van de Veen W, van Splunter M, Biol D, Akdis CA. Th17 and Th22 cells: a confusion of antimicrobial response with tissue inflammation versus protection. J Allergy Clin Immunol 2012;129:1438-49.
• 5. Hazenberg MD, Spits H. Human innate lymphoid cells. Blood 2014;124:700-9.

Terms in the title (9)： IL-22 ,  シグナル伝達 ,  MUC1 ,  発現 ,  鼻ポリープ ,  合併 ,  慢性副鼻腔炎 ,  病態 ,  調節