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J-GLOBAL ID：201702237909021085   Reference number：17A0488182

Downregulation of microRNA-100/microRNA-125b is associated with lymph node metastasis in early colorectal cancer with submucosal invasion

マイクロRNA-100/マイクロRNA-125bのダウンレギュレーションは粘膜下浸潤のある初期結腸直腸癌でリンパ節転移と関係する

Author (13)： Fujino Yasuteru (Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Takeishi Shunsaku (Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Nishida Kensei (Department of Pathophysiology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Okamoto Koichi (Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Muguruma Naoki (Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Kimura Tetsuo (Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Kitamura Shinji (Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Miyamoto Hiroshi (Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Fujimoto Akiko (Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Higashijima Jun (Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Shimada Mitsuo (Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Rokutan Kazuhito (Department of Pathophysiology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan) ,  Takayama Tetsuji (Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 108  Issue： 3  Page： 390-397  Publication year： 2017 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *antisense RNA ,...
Semi thesaurus term： *microRNA-125b ,...

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Author keywords (5)： Cancer invasion ,  colorectal cancer with submucosal invasion ,  lymph node metastasis ,  miR-100 ,  miR-125b

JST classification (4)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Tumors(=neoplasms)of digestive system  (GH04000D) ,  Blood cell tumors(=neoplasms)  (GK04000M) ,  Biological function  (EB04020F)

Reference (28)：

• Tanaka S, Oka S, Chayama K. Colorectal endoscopic submucosal dissection: present status and future perspective, including its differentiation from endoscopic mucosal resection. J Gastroenterol 2008; 43: 641-51.
• Kitajima K, Fujimori T, Fujii S et al. Correlations between lymph node metastasis and depth of submucosal invasion in submucosal invasive colorectal carcinoma: a Japanese collaborative study. J Gastroenterol 2004; 39: 534-43.
• Watanabe T, Itabashi M, Shimada Y et al. Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2014 for treatment of colorectal cancer. Int J Clin Oncol 2015; 20: 207-39.
• Pimentel-Nunes P, Dinis-Ribeiro M, Ponchon T et al. Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2015; 47: 829-54.
• Fisher DA, Shergill AK, Early DS, Comm ASP. Role of endoscopy in the staging and management of colorectal cancer (vol 78, pg 8, 2013). Gastrointest Endosc 2013; 78: 559.

Terms in the title (7)： マイクロRNA-125b ,  ダウンレギュレーション ,  粘膜 ,  浸潤 ,  初期 ,  結腸直腸癌 ,  リンパ節転移