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J-GLOBAL ID：201702238724488832   Reference number：17A1821988

RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1

RBPJ/CBF1はL3MBTL3/MBT1と相互作用するヒストンデメチラーゼKDM1A/LSD1を介してNotchシグナル伝達の抑制を促進する【Powered by NICT】

Author (28)： Xu Tao (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Park Sung-Soo (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Giaimo Benedetto Daniele (Institute of Biochemistry, University of Giessen, Giessen, Germany) ,  Hall Daniel (Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA) ,  Ferrante Francesca (Institute of Biochemistry, University of Giessen, Giessen, Germany) ,  Ho Diana M (Department of Cell Biology, Harvard Medical School, Boston, MA, USA) ,  Hori Kazuya (Department of Cell Biology, Harvard Medical School, Boston, MA, USA) ,  Anhezini Lucas (Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA) ,  Ertl Iris (Cancer and Human Molecular Genetics, Bellvitge Biomedical Research Institute, L’Hospitalet de Llobregat, Barcelona, Spain) ,  Bartkuhn Marek (Institute for Genetics, University of Giessen, Giessen, Germany) ,  Zhang Honglai (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Milon Elena (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Ha Kimberly (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Conlon Kevin P (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Kuick Rork (Center for Cancer Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA) ,  Govindarajoo Brandon (Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA) ,  Zhang Yang (Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA) ,  Sun Yuqing (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Dou Yali (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Basrur Venkatesha (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Elenitoba-Johnson Kojo SJ (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Nesvizhskii Alexey I (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ,  Nesvizhskii Alexey I (Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA) ,  Ceron Julian (Cancer and Human Molecular Genetics, Bellvitge Biomedical Research Institute, L’Hospitalet de Llobregat, Barcelona, Spain) ,  Lee Cheng-Yu (Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA) ,  Borggrefe Tilman (Institute of Biochemistry, University of Giessen, Giessen, Germany) ,  Kovall Rhett A (Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA) ,  Rual Jean-Francois (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA)
Material： EMBO Journal  (EMBO J)
Volume： 36  Issue： 21  Page： 3232-3249  Publication year： 2017 
JST Material Number： A0911B  ISSN： 0261-4189  CODEN： EMJODG  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Notch signaling is an evolutio...

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Thesaurus term： repressor ,  demethylation ,  *interaction ,  *Notch receptor ,  complex (substance) ,  D. melanogaster ,  Transcription repression ,  target gene ,  ligand binding ,  *Notch signaling ,  *lysine demethylase 1 ,  *Histone Demethylases ,  Drosophila ,  Caenorhabditis elegans ,  Diptera ,  invertebrate ,  Rhabditida
Semi thesaurus term： Drosophila ,  Caenorhabditis elegans ,  後生動物 , 【Automatic Indexing@JST】

Author keywords (4)： KDM1A ,  L3MBTL3 ,  Notch signaling ,  RBPJ

JST classification (2)： Cell physiology in general  (EF02010S) ,  Function of cell components  (EF03060C)

Terms in the title (6)： CBF1 ,  相互作用 ,  ヒストンデメチラーゼ ,  LSD1 ,  Notchシグナル ,  促進